DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nup98-96 and Ncoa5

DIOPT Version :9

Sequence 1:	NP_001262885.1	Gene:	Nup98-96 / 42816	FlyBaseID:	FBgn0039120	Length:	1960	Species:	Drosophila melanogaster
Sequence 2:	NP_001100013.1	Gene:	Ncoa5 / 296372	RGDID:	1307702	Length:	578	Species:	Rattus norvegicus

Alignment Length:	211	Identity:	55/211 - (26%)
Similarity:	75/211 - (35%)	Gaps:	70/211 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KPAAPAFGNTSTFAAQPAQQSLF------GAAATPAQPA---------------GGLFGANTSTG 80
            :|...|.|  |:...||:.|.|.      .|..|||.|.               .|...||:|:.
  Rat   388 QPLGAASG--SSLKTQPSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGAVAANSSSA 450

  Fly    81 FGSTATA----QPTAFGAFSQPQQTSNIFGSTQTAASTSLFGQSTLPAFGAAKPTMTAFGQTAAA 141
            ..|.||.    |..:..|.|||||.....|:    ...::.||:     |:|:    ..|....|
  Rat   451 SPSVATGSSQNQNFSTAANSQPQQRPQASGN----QPPNIVGQA-----GSAR----NMGPRPGA 502

  Fly   142 QPTGSLFGQPAAATSTTGFGGFGTSAPTTTNVFGSGTASAFAQPQATAVGASGVN-TGTAVAKYQ 205
             |:..|||||:                       |..|.|........|.::|:| ...:|.|
  Rat   503 -PSQGLFGQPS-----------------------SRLAPASNMASQRPVSSTGINFDNPSVQK-- 541

  Fly   206 PTIGTDTLMKSGQANS 221
               ..|||::||.|.|
  Rat   542 ---ALDTLIQSGPALS 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup98-96	NP_001262885.1	Nucleoporin_FG	395..481	CDD:316182
		Nucleoporin2	888..1027	CDD:309287
		Nup96	1484..1762	CDD:314912
		Nucleoporin_FG	<1..74	CDD:316182	14/57 (25%)
		Nucleoporin_FG	50..164	CDD:316182	36/138 (26%)
		Nucleoporin_FG	254..318	CDD:316182
		NupH_GANP	316..>522	CDD:318883
Ncoa5	NP_001100013.1	HisS	<185..255	CDD:223202
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900