Protein Alignment Nup98-96 and nup45

DIOPT Version :9

• Sequence 1: NP_001262885.1
• Gene: Nup98-96 / 42816
• FlyBaseID: FBgn0039120
• Length: 1960
• Species: Drosophila melanogaster
• Sequence 2: NP_593058.1
• Gene: nup45 / 2541890
• PomBaseID: SPAC22G7.09c
• Length: 425
• Species: Schizosaccharomyces pombe
• Alignment Length: 585
• Identity: 147/585 - (25%)
• Similarity: 195/585 - (33%)
• Gaps: 194/585 - (33%)

  Fly   281 LFGSTAQPSTGLFGQTVTENKSMFGTTAFGQQPATNNAFGAATQQNNFLQKPFGATTTTPFAAPA 345
            :||....||   ||.|.|:|::. ||:| |....::|.||..||.|            ||
pombe     1 MFGLNKTPS---FGSTGTQNQNT-GTSA-GTGLFSSNTFGNNTQAN------------TP----- 43

  Fly   346 ADASNPFGAKP--AFGQ-----GGSLFGQAP-ATSAAPAFGQTNTGFGGFGTTAGATQQSTLFGA 402
              ||..||...  ||||     ||||||..| |||..|..                    .|||.
pombe    44 --ASTGFGGVTGGAFGQTKPQTGGSLFGNKPNATSTTPGL--------------------NLFGQ 86

  Fly   403 TPAADPNKSAFGLGTAASAATTGFGF------GAPATSTAGGGLFGNKPATSFAAPTFGATSTAS 461
            .|.|.|..|.||..|....|..|. |      ..||.:...|||||    .|....|...|..|.
pombe    87 NPQAAPGGSLFGASTTKPQAPGGL-FNQNQTQAQPAQAAPTGGLFG----LSGQNQTQSQTQPAQ 146

  Fly   462 TPFSNFGLNTSTAATGGGLFNSGLNKPATSGFGGFGATSAAPLNFNAGNTGGSLFGNTAKPGGGL 526
            ...|.||  .|...|.||||:.  |:|.||.||.|                     :|.....||
pombe   147 ANTSLFG--QSNIGTTGGLFDQ--NRPNTSTFGQF---------------------STQPASAGL 186

  Fly   527 FGGGTTTLGGTGAAPTGGLFGGGTTSFGGVGGSLGGGGFGMGTNNSLTGGIMGAQPTLGIMTPSH 591
            ||..|...|.|                          |||:..|...|.....||     ..||.
pombe   187 FGQSTQPSGST--------------------------GFGLSNNTQTTPFFSAAQ-----QQPST 220

  Fly   592 QPIHQQILARVTSPYG-------------DSPIFKDLKLSSEADATRATNPAAQQAVLDLTSNQY 643
            ..:........|:.|.             |..||..::|:.|......|       |.:|..
pombe   221 TQLPSNPAINATTRYSSLNANTQKFLDDLDKEIFSQIQLAEELQTKLGT-------VSELVE--- 275

  Fly   644 KISTSNNPAPMKVKALGSTLNRKSLFDGLEEFDASVEGFNLKPSAKRLVIKPKVKSVEGGNPSSS 708
              |..|:.|  :|:...|:::...|.|..|     :|      :.||:|    .:.......||.
pombe   276 --SVPNDVA--EVQRRLSSVSTALLIDSDE-----IE------TTKRVV----DEDTSNARISSR 321

  Fly   709 IGSAPNTPQSRPKGATPNKERESFSGAIPSEPLPPAGNSPGATNGRESQDNGRRESWLHPNNLEK 773
            |.....||     |||                .|.|.|.|......:..:|.::.:.|:...:.:
pombe   322 ILDVFKTP-----GAT----------------YPFASNDPLMNYFEQFTENAKKRTDLYAATIGE 365

  Fly   774 VRQHNIQTGMDQGSPHNSTLNELVPRKPLDTYRPSSTVRLSVSTIPENPFEDQSSTIARRETFTS 838
            :.||..|.   :.:|.|::     |...|.|.:....:.:::|    |.|......:.|.:..||
pombe   366 LEQHLEQV---ETTPQNNS-----PEALLKTIKEEHKLFMALS----NRFAQVHDEVKRLQVNTS 418

  Fly   839  838
            pombe   419  418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup98-96	NP_001262885.1	Nucleoporin_FG	395..481	CDD:316182	31/91 (34%)
		Nucleoporin2	888..1027	CDD:309287
		Nup96	1484..1762	CDD:314912
		Nucleoporin_FG	<1..74	CDD:316182
		Nucleoporin_FG	50..164	CDD:316182
		Nucleoporin_FG	254..318	CDD:316182	13/36 (36%)
		NupH_GANP	316..>522	CDD:318883	68/219 (31%)
nup45	NP_593058.1	Nucleoporin_FG2	12..>414	CDD:292589	139/565 (25%)
		Nucleoporin_FG	43..142	CDD:290362	42/130 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R852
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840