DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tst and AT3G46960

DIOPT Version :9

Sequence 1:	NP_001262884.1	Gene:	tst / 42813	FlyBaseID:	FBgn0039117	Length:	1197	Species:	Drosophila melanogaster
Sequence 2:	NP_190280.5	Gene:	AT3G46960 / 823849	AraportID:	AT3G46960	Length:	1347	Species:	Arabidopsis thaliana

Alignment Length:	1251	Identity:	471/1251 - (37%)
Similarity:	674/1251 - (53%)	Gaps:	160/1251 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VELDLEAVGANANNSMSMQREPGLLEDATRGSHSNFPFWPGGFDEQR--QQIAALDVSNFQFGDK 129
            ||:||........:|....|..|..:|..|||.:|.||.|||.::.:  :::....||:.|:..:
plant   130 VEVDLSEQMYGDQDSGFFPRMVGPPKDFLRGSVNNRPFRPGGLEDSQSSERVLPEGVSSGQWVQE 194

  Fly   130 LL------TVPPGFSSGYDFFQSQSVTLPPVVADPSNVDLLENLE-----------------QDL 171
            ||      ||||.|        .||:.|..::..|....:.|:..                 .||
plant   195 LLNGGPAQTVPPSF--------KQSLDLGDLMPYPQTWSVYEDHSSHGNASDENSSKLSIQFDDL 251

  Fly   172 DVQEWMKLTRSE-----ETSSTGTPKSPKQ--SNVQLPSEEFRDVD------DHIMKADLKPVLN 223
            ..:.|.:.|.||     .|:.:.:||:..:  :...:.:|..:.::      |.|:.:....:::
plant   252 FKKAWEEDTFSELEGDDHTAGSESPKAEAEPDAKASISNEVSKGLETDVTVLDEILSSAKTAIMS 316

  Fly   224 ISTTTKNF-----KSDWAEMVDISQPINNFKEQIPCPAMDFPFELDVFQKQAILKLEQRQYVFVA 283
            ....|.:.     |..||...|.....:.|.|.:|..|::||||||.|||:||..||:.:.||||
plant   317 EEAVTGSSDKQLRKEGWATKGDSQDIADRFYELVPDMAIEFPFELDNFQKEAICCLEKGESVFVA 381

  Fly   284 AHTSAGKTVVAEYAIALSKRDLTRTIYTSPIKALSNQKYRDFRKTFKDVGLITGDLQIEPTASCL 348
            ||||||||||||||.||:.:..||.:||:|||.:||||||||...| ||||:|||:.|.|.||||
plant   382 AHTSAGKTVVAEYAFALATKHCTRAVYTAPIKTISNQKYRDFCGKF-DVGLLTGDVSIRPEASCL 445

  Fly   349 IMTTEILRSMLYCGSDVTRDLEWVIFDEVHYINNPERGHVWEEVIILLPEHVNIIMLSATVPNTL 413
            ||||||||||||.|:|:.||:||||||||||:|:.|||.|||||||:||.|:|.::||||||||.
plant   446 IMTTEILRSMLYRGADIIRDIEWVIFDEVHYVNDVERGVVWEEVIIMLPRHINFVLLSATVPNTF 510

  Fly   414 ELADWVGSTKKRKVYVISTLKRPVPLTHFL-YTGAGGK-SRDDIFL---LVDAQGKYLQGNYEK- 472
            |.|||:|.||::::.|..|.||||||.|.| |:|...| ..:::||   :.||:....:.|...
plant   511 EFADWIGRTKQKEIRVTGTTKRPVPLEHCLFYSGELYKVCENEVFLSKGIKDAKDSQKKKNSNAV 575

  Fly   473 AVERKKEMQGKAKGGGGGPRN---HLNAKQEQYT---------------------------WIGL 507
            :|..|::|...|...|...:.   |...||.:::                           |:.|
plant   576 SVAPKQQMGSSAHQDGSKSQKHEAHSRGKQNKHSSVKDVGKSSYSGNSQNNGAFRRSAASNWLLL 640

  Fly   508 IDFLRRSNMMPVVAFTLSRNRCDSNLAALQSVDLNTEKEKGAVQKFFLQCLAKLKPPDRTIPQVL 572
            |:.|.:.:::|||.|..|:|.||....||...||.:..||..::.|..:..::||..||.:||||
plant   641 INKLSKMSLLPVVVFCFSKNYCDRCADALTGTDLTSSSEKSEIRVFCDKAFSRLKGSDRNLPQVL 705

  Fly   573 VLKDALERGIGVHHSGILPILKEIVEMLFQNGLVKLLFATETFAMGVNMPARTVVFDSCKKFDGL 637
            .|:..|.|||||||:|:|||:||:|||||..|::|:||:|||||||||.||||||||:.:||||.
plant   706 RLQSLLHRGIGVHHAGLLPIVKEVVEMLFCRGVIKVLFSTETFAMGVNAPARTVVFDALRKFDGK 770

  Fly   638 EMRNLKPGEYIQMAGRAGRRGHDETGTAIIMCKGSVPPSMELRPMILGLPEKLQSQFILRYAVIL 702
            |.|.|.||||.||||||||||.|:|||.::||:..||...:||.:|:|...:|:|||.|.|.:||
plant   771 EFRQLLPGEYTQMAGRAGRRGLDKTGTVVVMCRDEVPDESDLRRVIVGSATRLESQFRLTYIMIL 835

  Fly   703 TCLRIESIKVEDIMKFSFKEFNLKLQLPTQQKQLRLAEDKFAMLPTLGEHL-----QPLV-NFYD 761
            ..||:|.:||||::|.||.||:.:.:||.:|:.|.:...    |||  :|:     :|.: ::||
plant   836 HLLRVEELKVEDMLKRSFAEFHAQKKLPEKQQLLMIKRS----LPT--KHIECIKGEPAIEDYYD 894

  Fly   762 KAVEYWKEKHRIMKFVVTQPKIQKELKAGRVIVITQGKHY-NKLAILLNTKSVPGKDTIYKVLVL 825
            ..:|..:..:::.:.|:..|..|..|..|||:|:..|... |.|.|:|...|...:.  |.|||:
plant   895 MYMEANEYNNKMSEAVMQSPYAQSFLVQGRVVVMKSGMGIDNLLGIVLKGPSNTNRQ--YVVLVI 957

  Fly   826 DHQFKAKDSNSLQQG----------------------ELYYKILS-----LTPRNMTFQPVGIG- 862
            ..:....:.|.:..|                      |.|.|..|     :....:.:..|..|
plant   958 KSEIPPPEKNMVSIGKKSSDPSQGYFIAPKSKRGFEEEFYTKPSSRKGPVVIKIELPYHGVAAGV 1022

  Fly   863 GHTVLDIKAIDIISITKSTLKVDADAIIRNWEQRQLERFKDSPPSGSVVKAVTELNQLNESYIDN 927
            |:.|......:.:.|..|.:|:|.   :|..|......|..:      |:.:.:|......:...
plant  1023 GYEVKGFDNKEFLCICDSKIKIDQ---VRLLEDGNKAAFSQT------VQQLLDLKSDGNKFPPA 1078

  Fly   928 PDNIKYVNLSKEIIVNADSEVAMLNYV-DHLLRKVGEFLPHTNIAGFEQEFAKVYERRMLEIHIE 991
            .|.:|.:.|.       |:|:....|. .:||:|:.....| .....|:......|.:..:..::
plant  1079 LDPVKDLKLK-------DAELVETYYKWTNLLQKMSMNKCH-GCVKLEEHMKLAREIKKHKTDLK 1135

  Fly   992 ELRFKNSARNLTLYPDYCNKLKVLRALKYIDELDEVTLKGKVACEMGQ-NELLITELILCNMFND 1055
            :|.|:.|...|...|.:..::.||:.:..||:...|.:||:|||||.. .||:.|..:..|.|.:
plant  1136 DLEFQMSDEALLQMPAFQGRIDVLKNIGCIDDDLVVQIKGRVACEMNSGEELICTVCLFENQFEE 1200

  Fly  1056 LEPAEIAALLSGLVFQAKMQDKPVIPEALKECVAAFEQINDT-ILAEEQRFQAAIETD------N 1113
            |||.|..|::|..|||.|....|.:...|.:   |.:::.|| |...|.:.|..::.|      .
plant  1201 LEPEEAVAIMSAFVFQQKNTSAPTLTPKLAK---AKQRLYDTAIRLGELQAQYNLQIDPEEYAQE 1262

  Fly  1114 RLNFGLLEVVYEWARNKPFAEIMKLTTVQEGIIVRCIQQLNETLRDVKTAAIRIGNPGLQSKMEE 1178
            .|.|||:|||||||:..|||||.:||.|.||:|||.|.:|:||.|:.|.||..:||..|..||:.
plant  1263 NLKFGLVEVVYEWAKGTPFAEICELTDVPEGLIVRTIVRLDETCREFKNAAAIMGNSALHKKMDA 1327

  Fly  1179 ASAAIKRDIVFTASLY 1194
            ||.||||||||.||||
plant  1328 ASNAIKRDIVFAASLY 1343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tst	NP_001262884.1	Dob10	193..1194	CDD:226947	428/1093 (39%)
		DEAD	267..414	CDD:278688	104/146 (71%)
		HELICc	578..658	CDD:197757	59/79 (75%)
		rRNA_proc-arch	715..996	CDD:289976	67/316 (21%)
		DSHCT	1025..1188	CDD:285374	76/170 (45%)
AT3G46960	NP_190280.5	Dob10	264..1343	CDD:226947	431/1107 (39%)
		DEAD	365..509	CDD:278688	102/144 (71%)
		HELICc	711..791	CDD:197757	59/79 (75%)
		rRNA_proc-arch	848..1142	CDD:289976	68/318 (21%)
		DSHCT	1169..1337	CDD:285374	76/170 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	215	1.000	Domainoid score	I756
eggNOG	1	0.900	-	-		E1_COG4581
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H123971
Inparanoid	1	1.050	681	1.000	Inparanoid score	I144
OMA	1	1.010	-	-		QHG54620
OrthoDB	1	1.010	-	-		D176060at2759
OrthoFinder	1	1.000	-	-		FOG0004949
OrthoInspector	1	1.000	-	-		oto3513
orthoMCL	1	0.900	-	-		OOG6_100340
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3492
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740