Protein Alignment tst and Mtr4

DIOPT Version :10

• Sequence 1: NP_524465.1
• Gene: tst / 42813
• FlyBaseID: FBgn0039117
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Alignment Length: 1127
• Identity: 373/1127 - (33%)
• Similarity: 578/1127 - (51%)
• Gaps: 152/1127 - (13%)

  Fly   141 YDFFQSQSVTLPPVVADPSNVDLLENLEQDLDVQEWMKLTRSEE-TSSTGTPKSPKQSNVQLPSE 204
            :|.|...:.::||...:........:..:..:.::....|.|:| |||.|.....|....:.|::
  Fly     7 FDCFDEVTPSVPPPALNQEEKPSGSSASKKGNKRQADGTTASKEATSSKGAEGDDKGDVTEEPTK 71

  Fly   205 EFR----------------------DVDDHIMKADLKP--VLNISTTTKNFKSDWAEMVDISQPI 245
            ..:                      |:||......|:.  |.::....|:...:.|...|
  Fly    72 RLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIVTHLLDAPKSCTHEVAAHPD----- 131

  Fly   246 NNFKEQIP------CPAMDFPFELDVFQKQAILKLEQRQYVFVAAHTSAGKTVVAEYAIALSKRD 304
               :|.||      .||.::||.||.||:||||.::..|.|.|:||||||||||||||||.|...
  Fly   132 ---QEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYAIAKSLAA 193

  Fly   305 LTRTIYTSPIKALSNQKYRDFRKTFKDVGLITGDLQIEPTASCLIMTTEILRSMLYCGSDVTRDL 369
            ..|.|||:|||||||||:|:|...||||||:|||:.|.|:||||||||||||:|||.||::.|::
  Fly   194 KQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRGSEIMREV 258

  Fly   370 EWVIFDEVHYINNPERGHVWEEVIILLPEHVNIIMLSATVPNTLELADWVGSTKKRKVYVISTLK 434
            .||:|||:||:.:.|||.||||.:||||::|..:.||||:||..:.|:||....|:..:|:.|..
  Fly   259 GWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTDY 323

  Fly   435 RPVPLTHFLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAV----ERKKEMQGKAKGGGGGPRNHL 495
            ||.||.|:::. |||   |.|.|:||.:|::.:.|:..|:    ...:..:|..||..||.:. .
  Fly   324 RPTPLQHYIFP-AGG---DGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGGIKG-T 383

  Fly   496 NAKQEQYTWIGLIDFLRRSNMMPVVAFTLSRNRCDSNLAALQSVDLNTEKEKGAVQKFFLQCLAK 560
            ||.|...  ..::..:...|..||:.|:.|:..|:.....:..:|.||..||..|.:.|...:..
  Fly   384 NAGQTNI--FKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDV 446

  Fly   561 LKPPDRTIPQVLVLKDALERGIGVHHSGILPILKEIVEMLFQNGLVKLLFATETFAMGVNMPART 625
            |...||.:|||..:...|.||||:||.|:||||||.:|:||..||:|.||||||||||:||||||
  Fly   447 LTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPART 511

  Fly   626 VVFDSCKKFDGLEMRNLKPGEYIQMAGRAGRRGHDETGTAIIMCKGSVPPSMELRPMILGLPEKL 690
            |:|.:.:||||.:.|.:..||||||||||||||.|:.|..|:|....|.|::. |.::.|..:.:
  Fly   512 VLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVG-RDIVQGKADPI 575

  Fly   691 QSQFILRYAVILTCLRIESIKVEDIMKFSFKEFNLKLQLP-----TQQKQLRL------AEDKFA 744
            .|.|.|.|.::|..||:|.|..|.:::.||.:|..:..||     .:||.|.|      .|...|
  Fly   576 NSAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIA 640

  Fly   745 MLPTLGEHLQPLVNFYDKAVEYWKEKHRIMKFVVTQPK-IQKELKAGRVIVITQGKHYNKLAILL 808
            ..    .|::..::.:.|....|          :|:|: :...|:.||::.:..|.......|:|
  Fly   641 SY----HHIRSQLDQHGKQFRQW----------ITKPQYLLPFLQPGRLVKVAAGSQEYDWGIVL 691

  Fly   809 NTKSVPGKDTIYKVLVLDHQFKAKDSNSLQQGELYYKILSLTPRNMTFQPVGIGGHTVLDIKAID 873
            |.|.   :|...|     :..||:.|.::   ::...:.....:....:|........:::..:.
  Fly   692 NFKK---QDQSRK-----NPLKAEPSVTI---DVLLHVSEAAAKTGDTEPCKPNERGCMEVVPVA 745

  Fly   874 IISITK-STLKV-------DAD---AIIRNWEQRQLERFKDSPPSGSVVKAVTELNQLNESYIDN 927
            ...||: |:::|       .||   |:::..::.: :||...||   |:..:.::|..:..:.|
  Fly   746 HTLITQISSIRVYFPNDLRSADNRRAVLKTIQEAK-KRFPLGPP---VLNPIDDMNIKDREFRD- 805

  Fly   928 PDNIKYVNLSKEIIVNADSEVAMLNYVDHLLRKVGEFLPHTNIAGFEQEFAKVYERRMLEIHIEE 992
                         |||..|:... ...:|.|.|..|         .|:...:..::..|:..:::
  Fly   806 -------------IVNTISQFEK-RLEEHPLHKSPE---------LERIHRRYQDKVTLQKQLQD 847

  Fly   993 LRFK-NSARNLTLYPDYCNKLKVLRALKYIDELDEVTLKGKVACEMGQ-NELLITELILCNMFND 1055
            |:.: .:||:|....:..::.:|||.:.|....|.:..||:||||:.. :|||:||:|...:|||
  Fly   848 LKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADELLMTEMIFNGVFND 912

  Fly  1056 LEPAEIAALLSGLVFQAKMQDKPVIPEALKECVAAFEQINDTI--LAEEQRFQAAIETDNRLNFG 1118
            |...:..||||..|...|.          .|.|.:..:::..:  :.:..|..|.:.|:.:|:..
  Fly   913 LTAPQAVALLSCFVCDEKS----------SESVKSATELSGPLRSMQDLARRIAKVSTECKLDLD 967

  Fly  1119 -----------LLEVVYEWARNKPFAEIMKLTTVQEGIIVRCIQQLNETLRDVKTAAIRIGNPGL 1172
                       |::||..|.:...|..:.|:|.:.||.|:||:::|.|.||.:..|:..|||..|
  Fly   968 ADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIGNTDL 1032

  Fly  1173 QSKMEEASAAIKRDIVFTASLY 1194
            ::|..|....:||||||.||||
  Fly  1033 ENKFSEGIRLLKRDIVFAASLY 1054

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tst	NP_524465.1	Ski2_N	33..143	CDD:465562	0/1 (0%)
		Dob10	258..>755	CDD:443638	235/511 (46%)
		rRNA_proc-arch	713..999	CDD:463813	56/309 (18%)
		DSHCT	1025..1188	CDD:462374	55/176 (31%)
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	341/973 (35%)