Protein Alignment tst and mtrex

DIOPT Version :10

• Sequence 1: NP_524465.1
• Gene: tst / 42813
• FlyBaseID: FBgn0039117
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: NP_999933.1
• Gene: mtrex / 406795
• ZFINID: ZDB-GENE-040426-2854
• Length: 1034
• Species: Danio rerio
• Alignment Length: 1101
• Identity: 383/1101 - (34%)
• Similarity: 571/1101 - (51%)
• Gaps: 178/1101 - (16%)

  Fly   185 TSSTGTPKS-------------PKQSNVQLPSEEFRDVDDH-------IMKADLKPV----LNIS 225
            :|....|||             |:..:..|..   ||.||.       ..:..|:.|    :|:|
Zfish    20 SSKKAAPKSAANAGKTPDKAGKPQGDSASLRK---RDADDDGPDEMLLGKRQKLETVSAEEINLS 81

  Fly   226 TTTKNFKSDWAEMV-----DISQPINN----FKEQIPCPAMDFPFELDVFQKQAILKLEQRQYVF 281
            ......||:..|.|     ::..|.|.    .|.::...|.::||.||.||::|||.::..|.|.
Zfish    82 ELMPKVKSEQVETVEGCTHEVVLPANEEYTPLKPRVGKAAKEYPFILDPFQREAILCIDNNQSVL 146

  Fly   282 VAAHTSAGKTVVAEYAIALSKRDLTRTIYTSPIKALSNQKYRDFRKTFKDVGLITGDLQIEPTAS 346
            |:|||||||||.|||||||:.|:..|.|:|||||||||||||:..:.|:||||:|||:.|.||||
Zfish   147 VSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTAS 211

  Fly   347 CLIMTTEILRSMLYCGSDVTRDLEWVIFDEVHYINNPERGHVWEEVIILLPEHVNIIMLSATVPN 411
            ||:|||||||||||.||:|.|::.||||||:||:.:.|||.||||.|||||::|:.:.|||||||
Zfish   212 CLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHHVFLSATVPN 276

  Fly   412 TLELADWVGSTKKRKVYVISTLKRPVPLTHFLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAVE- 475
            ..:.|:|:....|:..:|:.|..||.||.|:::. |||   |.:.|:||..|::.:.|:..|::
Zfish   277 ARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFP-AGG---DGLHLVVDENGEFREDNFNTAMQV 337

  Fly   476 ------------RKKEMQGKAKGGGGGPRNHLNAKQEQYTWIGLIDFLRRSNMMPVVAFTLSRNR 528
                        .|.:.:|: |||..||.|...          ::..:...|..||:.|:.|:..
Zfish   338 LRDAGDTGGNTGAKWDPKGR-KGGTKGPSNVFK----------IVKMIMERNFQPVIIFSFSKKE 391

  Fly   529 CDSNLAALQSVDLNTEKEKGAVQKFFLQCLAKLKPPDRTIPQVLVLKDALERGIGVHHSGILPIL 593
            |::....:..:|.||::||..|::.|......|...|:.:|||..:...|:||||:||.|:||||
Zfish   392 CEAYALQVSKLDFNTDEEKKLVEEVFNNATDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPIL 456

  Fly   594 KEIVEMLFQNGLVKLLFATETFAMGVNMPARTVVFDSCKKFDGLEMRNLKPGEYIQMAGRAGRRG 658
            ||.:|:||..||:|.||||||||||:|||||||:|.|.:||||.:.|.:..||||||:|||||||
Zfish   457 KETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRG 521

  Fly   659 HDETGTAIIMCKGSVPPSMELRPMILGLPEKLQSQFILRYAVILTCLRIESIKVEDIMKFSFKEF 723
            .||.|..|.|....:.|::. :.::.|..:.|.|.|.|.|.::|..||:|.|..|.:::.||.:|
Zfish   522 MDERGIVIFMVDEKMSPAVG-KQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQF 585

  Fly   724 NLKLQLPTQQKQLRLAEDKFAMLPTLGEHLQPLVNFY---------DKAVEYWKEKHR-IMKFVV 778
            .....:|....:::..|:::..:....|  :.:|.:|         .|.:|.:..|.| .:.|:
Zfish   586 QHYRAVPGVVDRMKKLEEEYNAIRIPKE--ESVVTYYKIRQQLAKLGKEIEEFIHKPRYCLPFL- 647

  Fly   779 TQP----KIQKE-LKAGRVIVITQGKHYNKLAILLNTKSVPGKDTIYKVLVLDHQFKAKDSNSLQ 838
             ||    |::|| |..|..:|:    ::.|.:   |.|:....|.::.|.||.|..|....|:..
Zfish   648 -QPGRLVKVKKEDLDFGWGVVV----NFQKKS---NVKAGGDLDPLFVVEVLVHCSKDSVKNAAT 704

  Fly   839 QGELYYKILSLTPRNMTFQPVGIGGHTVLDIKAIDIISITKSTLKVDADAIIRNWEQRQLERFKD 903
            :        |..|..    |...|...|:.:....|.||:...|.:..|  :|.::.||
Zfish   705 E--------SARPAG----PAEKGEMQVVPVILHLITSISSVRLYIPKD--LRPYDNRQ------ 749

  Fly   904 SPPSGSVVKAVTELNQLNESYIDNPDNIKYVNLSKEIIVNADSEVAMLNYVDHLLRKVGEFLPHT 968
                 |::|::.|:.:      ..||.|..::           .:..:...|..|:||.:
Zfish   750 -----SMLKSIQEVQK------RFPDGIPLLD-----------PIDDMGIKDPALKKVIQ----- 787

  Fly   969 NIAGFE--------------QEFAKVYERRML---EIHIEELRFKNSARNLTLYPDYCNKLKVLR 1016
            .:..||              :...|:.|::.|   :|...:...|.:...|.:....|.| :|||
Zfish   788 KVEAFEHRMYTHPLHSDPNLEAVYKLCEKKALIAGDIKAAKRELKKARTVLQMDELKCRK-RVLR 851

  Fly  1017 ALKYIDELDEVTLKGKVACEMGQ-NELLITELILCNMFNDLEPAEIAALLSGLVFQAKMQDKPVI 1080
            .|.:....|.:.:||:||||... :|||:||::...:||||...:..||||..|||....:.|.:
Zfish   852 RLGFATSSDVIEMKGRVACETSSGDELLLTEMMFNGLFNDLTAEQATALLSCFVFQENANEMPKL 916

  Fly  1081 PEAL-------KECVAAFEQINDTILAEEQRFQAAIETD-----NRLNFGLLEVVYEWARNKPFA 1133
            .|.|       :||.....:::         .:|.:|.|     |:....|::|||.||....|:
Zfish   917 TEQLGGPLRQMQECAKRIAKVS---------AEAKLEVDEDSYLNQFRPHLMDVVYTWANGSSFS 972

  Fly  1134 EIMKLTTVQEGIIVRCIQQLNETLRDVKTAAIRIGNPGLQSKMEEASAAIKRDIVFTASLY 1194
            :|.|:|.|.||.|:||:::|.|.||.:..||..|||..|::|.......|||||||.||||
Zfish   973 QICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFATGITKIKRDIVFAASLY 1033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tst	NP_524465.1	Ski2_N	33..143	CDD:465562
		Dob10	258..>755	CDD:443638	229/509 (45%)
		rRNA_proc-arch	713..999	CDD:463813	62/317 (20%)
		DSHCT	1025..1188	CDD:462374	63/175 (36%)
mtrex	NP_999933.1	Dob10	115..1006	CDD:443638	346/974 (36%)