DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tst and Suv3

DIOPT Version :9

Sequence 1:	NP_001262884.1	Gene:	tst / 42813	FlyBaseID:	FBgn0039117	Length:	1197	Species:	Drosophila melanogaster
Sequence 2:	NP_001303458.1	Gene:	Suv3 / 40543	FlyBaseID:	FBgn0037232	Length:	763	Species:	Drosophila melanogaster

Alignment Length:	909	Identity:	165/909 - (18%)
Similarity:	294/909 - (32%)	Gaps:	342/909 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 TRSEETSSTGTPKSPKQSNVQLPSEEF-RDVDDHIMKADLKPVLNISTTTKNFKS--------DW 235
            :|.:..::..|...|.|.:..:.||:. .::...:.||:|..:||..|..:..||        |:
  Fly    41 SRKKPETNLSTLFKPVQVHAYVDSEDVGSELSGKLEKAELLKILNKFTQRREIKSLCNENGLDDY 105

  Fly   236 AEMVDISQPINNFK------EQIPCPA-------------MD--FPFEL----DVF-------QK 268
            .:    .|...:|:      |.:|...             :|  ||:.|    .||       ..
  Fly   106 LQ----QQAFGSFRRFCIEAENLPVDLHITFSDITQGAGHIDDIFPYFLRHAKTVFPHLDCMDDL 166

  Fly   269 QAILKLEQ------------RQYVFVAAHTSAGKTVVAEYAIALSKRDLTRTIYTSPIKALSNQK 321
            :.|..|.|            |:.||.|..|::|||..|......:|..    :|..|:|.|:.:.
  Fly   167 KKISDLRQPANWYSNARAITRKIVFHAGPTNSGKTYHAMERYLSAKTG----VYCGPLKLLATEV 227

  Fly   322 YRDFRKTFKDVGLITGD-----LQIEPTASCLIMTTEILRSMLYCGSDVTRDLEWVIFDEVHYIN 381
            |....:......|:||:     :.....|:.:..|.|:        :.|....|..:.||:..|.
  Fly   228 YNKANERGTPCDLVTGEERKFGISESLPANHVACTVEM--------TSVNTPYEVAVIDEIQQIR 284

  Fly   382 NPERGHVWEEVII-LLPEHVNIIMLSATVPNTLEL----ADWVGSTKKRKVYVISTLKRPVPLTH 441
            :|:||..|....: |:.:.|::    ...|..|:|    .:..|.|.:.::|...|
  Fly   285 DPQRGWAWTRAFLGLIADEVHV----CGEPGALDLLQKICETTGETVEVRLYDRLT--------- 336

  Fly   442 FLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAVERKKEMQGKAKGGGGGPRNHLNAKQEQYTWIG 506
                                         |..||.                          |.:|
  Fly   337 -----------------------------ELTVEN--------------------------TALG 346

  Fly   507 LIDFLRRSNMMP---VVAFTLSRNRCDSNLAALQSVDLNTEKEKGAVQKFFLQCLAKLKPPDRTI 568
            .:|     |::|   :|.|:              ..|:.|
  Fly   347 SLD-----NIVPGDCIVCFS--------------KHDIYT------------------------- 367

  Fly   569 PQVLVLKDALERG--IGVHHSGILPILKEIVEMLFQN--GLVKLLFATETFAMGVNMPARTVVF- 628
                |.::...||  :.|.:.|:.|..|......|.:  ...|::.||:...||:|:..|.::|
  Fly   368 ----VSREIEARGKEVAVIYGGLPPGTKLAQAAKFNDPANSCKVMVATDAIGMGLNLSIRRIIFY 428

  Fly   629 ----DSCKKFDGLEMRNLKPGEYIQMAGRAGR-RGHDETG--TAI------------------IM 668
                .|..:....|:..:.....:|:|||||| |...|.|  ||.                  |.
  Fly   429 SLIKPSMNERGEREIDTISVSSALQIAGRAGRFRTQWEHGYVTAFKSEDLQTLQRILARTPEPIK 493

  Fly   669 CKGSVPPSMELRPMILGLPEKLQSQFILRYAVILTCLRIESIKVEDIMKF--SFKEFNLKLQL-- 729
            ..|..|.:.::......||....|..:..:..:.|        |:|.:.|  :.::|....::
  Fly   494 QAGLHPTADQIELYAYHLPSSSLSNLMDIFVNLCT--------VDDSLYFMCNIEDFKFLAEMIQ 550

  Fly   730 ---------------PTQQKQ-------LRLAED------------------KFAMLPTLGE--H 752
                           |..:|.       |::|..                  .|.:..|:.:  |
  Fly   551 HVALPLRARYVFCCAPINRKMPFVCSMFLKVARQYSRNEPITFDFIKKNCGWPFKLPKTILDLVH 615

  Fly   753 LQPLVNFYDKAVEYWKEKHRIMKFVVTQPKI---QKELKAGRVIVITQGKHYNKLAILLNTK-SV 813
            |:.:.:..|  :..|. .:|.|........:   ||||..    :|.||. :....:|.||: |.
  Fly   616 LEAVFDVMD--LYLWL-SYRFMDLFPEAAYVRDAQKELDE----IIQQGV-FQITRLLKNTEASQ 672

  Fly   814 PGKDTIYKVLVLDHQFKAKDSNSLQQGELYYKILS---LTPRNMTFQPVGIGGHTVLDIKAIDII 875
            .|:.:.|.:..:.| .|.....||.:|.|..::|:   |||..:
  Fly   673 DGETSNYAIRRITH-VKEPRLPSLSRGRLTERLLAQGLLTPGML--------------------- 715

  Fly   876 SITKSTLKVDADAIIRNWEQRQLERFKDSPPSGSVVKAVTELNQLNESYIDNPDNIKYVNLSKE 939
                |.|:       :.|:.:||.            |:.::.|:.:|..:::.|...|..:.::
  Fly   716 ----SELR-------KEWDAQQLG------------KSNSQSNENSEPVVNSDDEDNYSGIGRK 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tst	NP_001262884.1	Dob10	193..1194	CDD:226947	163/896 (18%)
		DEAD	267..414	CDD:278688	36/164 (22%)
		HELICc	578..658	CDD:197757	24/89 (27%)
		rRNA_proc-arch	715..996	CDD:289976	47/278 (17%)
		DSHCT	1025..1188	CDD:285374
Suv3	NP_001303458.1	DEXDc	193..323	CDD:238005	32/145 (22%)
		SrmB	195..507	CDD:223587	80/439 (18%)
		HELICc	<357..461	CDD:238034	28/146 (19%)
		SUV3_C	614..657	CDD:289293	11/49 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12131
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100