DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10375 and Dnajc8

DIOPT Version :9

Sequence 1:	NP_651185.1	Gene:	CG10375 / 42812	FlyBaseID:	FBgn0039116	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_036020285.1	Gene:	Dnajc8 / 68598	MGIID:	1915848	Length:	272	Species:	Mus musculus

Alignment Length:	234	Identity:	123/234 - (52%)
Similarity:	171/234 - (73%)	Gaps:	5/234 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YTEVKEIEKRDSVLTPSQQIDRLLRPGSTYFNLNPFEVLQIEPEVELADIKKRYRTLSILVHPDK 85
            :.:||:|||||||||...||:||.||||:||||||||||||:|||...:||||:|.|||||||||
Mouse    43 WCQVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDK 107

  Fly    86 NPDNQERAQMAFDIVSRSWKILENELTRKRCLEVYEEAKGRTDQMIAEKRKKLKKEGRPTEPIPE 150
            |.|:.:|||.||:.|.:::|:|.::..:||.|:|.:..|...:..:.|::|:|||||:||. :.|
Mouse   108 NQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTN-VEE 171

  Fly   151 DDPTKYKHAIYVMVMKLFADMERRRQKLDQRDQEERKRKRETEIEEEERIKADREWQQNFEESRQ 215
            |||..:|.|:|...|||||::|.:|::.:.::..||||:||.|||.:|:.|.:||||:||||||.
Mouse   172 DDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRD 236

  Fly   216 SRVNSWHDFQSGAGKSKKAKKQKHMTGMMVPPKFKPESR 254
            .||:||.:||:    :.|.||:|.....:.|||.|.|.|
Mouse   237 GRVDSWRNFQA----NTKGKKEKKNRTFLRPPKVKMEQR 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10375	NP_651185.1	DnaJ	54..109	CDD:99751	35/54 (65%)
Dnajc8	XP_036020285.1	CbpA	70..>257	CDD:225124	99/191 (52%)
Dnajc8	XP_036020285.1	DnaJ	76..131	CDD:99751	35/54 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847268
Domainoid	1	1.000	132	1.000	Domainoid score	I5091
eggNOG	1	0.900	-	-		E1_KOG1150
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40935
Inparanoid	1	1.050	261	1.000	Inparanoid score	I3090
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57796
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005829
OrthoInspector	1	1.000	-	-		oto95273
orthoMCL	1	0.900	-	-		OOG6_103567
Panther	1	1.100	-	-	LDO	PTHR15606
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5362
SonicParanoid	1	1.000	-	-		X5567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790