DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10375 and Gpalpp1

DIOPT Version :9

Sequence 1:	NP_651185.1	Gene:	CG10375 / 42812	FlyBaseID:	FBgn0039116	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_080453.2	Gene:	Gpalpp1 / 67467	MGIID:	1914717	Length:	346	Species:	Mus musculus

Alignment Length:	259	Identity:	65/259 - (25%)
Similarity:	90/259 - (34%)	Gaps:	89/259 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSSARDQPG--TSHDNFEEF-------------------YTEVKEIEKR-------------DSV 33
            :...|:.||  :|..|.||.                   |:...|.|||             ||
Mouse   125 NDKGREDPGQVSSFFNSEEAESGEDEDIVGPMPAKGPVNYSVTTEFEKRAQRMKEKLTKGDDDS- 188

  Fly    34 LTPSQQIDR-----LLRPGSTYFNLNP--FEVLQIEPEVELADIKKRYRTLSILVHPDKNPDNQE 91
               |:.|.|     .|.|....|.|.|  |:        ..||.|...|:    |..|...|.:.
Mouse   189 ---SKPITRESWMTELPPEMKEFGLGPRTFK--------RRADDKSGDRS----VWTDTPADRER 238

  Fly    92 RAQMAFDI-VSRSWKILENELT--RKRCLE---VYEEAKGRTDQMIAEKRKKLKKEGRPTEPIPE 150
            :|:...:. .|.|.|..||.|:  .||..|   .|.|:| |::.::....||||.:.      .|
Mouse   239 KAKEIQEARKSFSKKDEENILSGRDKRLAEQVSSYNESK-RSESLMDIHHKKLKSKA------AE 296

  Fly   151 DDPTKYKHAIYVMVMKLFADMERRRQKLDQRDQEERKRKRETEIEEEERIKADREWQQNFEESR 214
            |   |.||              :.|...| || ::.|..|..|.:::..||..||....|...:
Mouse   297 D---KNKH--------------QERIPFD-RD-KDLKVNRFDEAQKKALIKKSRELNTRFSHGK 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10375	NP_651185.1	DnaJ	54..109	CDD:99751	13/57 (23%)
Gpalpp1	NP_080453.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..283		44/174 (25%)
		GPALPP motif 1	7..12
		GPALPP motif 2	32..37
		GPALPP motif 3	91..96
		GPALPP motif 4	111..116
		DUF3752	210..338	CDD:289349	44/165 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..308		9/41 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930