DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10375 and dnj-30

DIOPT Version :9

Sequence 1:	NP_651185.1	Gene:	CG10375 / 42812	FlyBaseID:	FBgn0039116	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_491030.1	Gene:	dnj-30 / 171833	WormBaseID:	WBGene00001048	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	110/235 - (46%)
Similarity:	162/235 - (68%)	Gaps:	4/235 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FEEFYTEVKEIEKRDSVLTPSQQIDRLLRPGSTYFNLNPFEVLQIEPEVELADIKKRYRTLSILV 81
            ||.||.::|..|::|:.||..|||:|||:|||||.||||:|||||:.:.::...||:|:.||:||
Worm     4 FESFYQDLKSTEQQDAALTSEQQIERLLKPGSTYLNLNPYEVLQIDLDTDIEAAKKKYKKLSLLV 68

  Fly    82 HPDKNPDNQERAQMAFDIVSRSWKILENELTRKRCLEVYEEAKGRTDQMIAEKRKKLKKEGRPTE 146
            |||||||::|||..|||||.::.|.:|:.:...||.:.|.|.|.|...:::||::||:|:|: .:
Worm    69 HPDKNPDDRERADKAFDIVKKAIKQMEDPIELNRCKDCYTEGKARLAIVMSEKKRKLRKDGK-ED 132

  Fly   147 PIPEDDPTKYKHAIYVMVMKLFADMERRRQKLDQRDQEERKRKRETEIEEEERIKADREWQQNFE 211
            .|.||||..||.|:::.|.|:|||.|::|:.|::|..||::|..|..::..|:.|...|:.:|:|
Worm   133 VIEEDDPAGYKKALWITVTKVFADREKKRKMLEERANEEKRRSTEALVQAAEKRKLAEEFAKNYE 197

  Fly   212 ESRQSRVNSWHDFQSGAGKSKKAKKQKHMTG-MMVPPKFK 250
            |||..|..||.:||  |.|:||..|.|.:.| ...|||.|
Worm   198 ESRDERSGSWRNFQ--AKKAKKEDKGKTLKGAAFKPPKVK 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10375	NP_651185.1	DnaJ	54..109	CDD:99751	30/54 (56%)
dnj-30	NP_491030.1	DnaJ	41..97	CDD:197617	31/55 (56%)
dnj-30	NP_491030.1	DUF1451	<167..>206	CDD:388613	14/38 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164764
Domainoid	1	1.000	109	1.000	Domainoid score	I4005
eggNOG	1	0.900	-	-		E1_KOG1150
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40935
Inparanoid	1	1.050	221	1.000	Inparanoid score	I2283
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57796
OrthoDB	1	1.010	-	-		D1434217at2759
OrthoFinder	1	1.000	-	-		FOG0005829
OrthoInspector	1	1.000	-	-		oto20122
orthoMCL	1	0.900	-	-		OOG6_103567
Panther	1	1.100	-	-	LDO	PTHR15606
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5362
SonicParanoid	1	1.000	-	-		X5567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800