DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10214 and REXO2

DIOPT Version :9

Sequence 1:	NP_651184.1	Gene:	CG10214 / 42811	FlyBaseID:	FBgn0039115	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_056338.2	Gene:	REXO2 / 25996	HGNCID:	17851	Length:	237	Species:	Homo sapiens

Alignment Length:	174	Identity:	94/174 - (54%)
Similarity:	128/174 - (73%)	Gaps:	0/174 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 IVWMDLEMTGLDIEKDKILEVACIITDQDLNVKSEGPCFAINHPQEVYDSMNEWCMKHHYNSGLI 102
            :||:||||||||||||:|:|:||:|||.|||:.:|||...|..|.|:.|||::||.:||..|||.
Human    43 MVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLT 107

  Fly   103 DRCKSSDVNLEEASNLVLSYLEKNIPKRACPLGGNSVYTDRLFIMKFMPLVDAYLHYRIVDVSTI 167
            ...|.|.:.|::|....||::.:..|...|||.||||:.|:.|:.|:||....:|||||:||||:
Human   108 KAVKESTITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTV 172

  Fly   168 KELAKRWHPAILDSAPKKSFTHRSLDDIRESIKELAYYKANLFK 211
            |||.:||:|...:.||||:.:||:||||.||||||.:|:.|:||
Human   173 KELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFK 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10214	NP_651184.1	Orn	38..210	CDD:99838	92/171 (54%)
REXO2	NP_056338.2	Orn	43..215	CDD:99838	92/171 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160013
Domainoid	1	1.000	195	1.000	Domainoid score	I3168
eggNOG	1	0.900	-	-		E1_COG1949
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6447
Inparanoid	1	1.050	207	1.000	Inparanoid score	I3703
Isobase	1	0.950	-	0	Normalized mean entropy	S863
OMA	1	1.010	-	-		QHG63397
OrthoDB	1	1.010	-	-		D1079953at2759
OrthoFinder	1	1.000	-	-		FOG0003570
OrthoInspector	1	1.000	-	-		oto89189
orthoMCL	1	0.900	-	-		OOG6_103503
Panther	1	1.100	-	-	LDO	PTHR11046
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R875
SonicParanoid	1	1.000	-	-		X2441
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750