Protein Alignment Lsd-1 and PLIN2

DIOPT Version :9

• Sequence 1: NP_732904.2
• Gene: Lsd-1 / 42810
• FlyBaseID: FBgn0039114
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: XP_016869748.1
• Gene: PLIN2 / 123
• HGNCID: 248
• Length: 445
• Species: Homo sapiens
• Alignment Length: 430
• Identity: 89/430 - (20%)
• Similarity: 164/430 - (38%)
• Gaps: 105/430 - (24%)

  Fly    15 IDRIGSIPLVESSVKRVETIYDKVKNNNRLFSWYFETAEATI----SAAYETIQPAVKLFEPSIQ 75
            :.|:.::|||.|:...:.:.|...|:.........|.||..:    |.|..:..|.::..||.|.
Human    13 VTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIA 77

  Fly    76 RLDNVMCKSLDILEQRIPLVYLPPEMMYWNTKEYMS---DHLVRPVLKRADSV---------KQI 128
            ..:...||.||.:|:|:|::..|...:..|.|..::   |.:...|....|||         |..
Human    78 VANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTK 142

  Fly   129 G-----------------NAVLESPLTTYAAERIDGAFTVGDKFVDKYLVPIQTDQDQTDVKKLV 176
            |                 |.||.|.:....:..::.|.|..:..|::|| |:..::.:.:.||:
Human   143 GAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYL-PLTEEELEKEAKKV- 205

  Fly   177 SALNDNFSPIRQQLNRMFGHKSPQEDDNEAVPDERGAIKAIHHGQRFSRKLKRRLTQRTIAEARA 241
                :.|..:::                   |.....:.::      |.||..|..|:.::..:.
Human   206 ----EGFDLVQK-------------------PSYYVRLGSL------STKLHSRAYQQALSRVKE 241

  Fly   242 LKKQSKEAIHVLFYAAELIATDPK------QAVQKAKE----LWV-------YLSADEPENQARP 289
            .|::|::.|..|.....||....|      |.:|.|::    .||       |...||
Human   242 AKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDE------- 299

  Fly   290 ATLEQLIVLLTRESARRVVHLVNFSAHVAAN----IPRNLAHTTTEVAHHIIYINHRIITISRLD 350
            :...:.|...|...||.:...:..:.|...:    :|:|:    .:.|.|:..:...|.::.|
Human   300 SHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNI----QDQAKHMGVMAGDIYSVFR-- 358

  Fly   351 KVKTIS-KEEAESLFKRMLAFYGSLQGLTNAYLERVASFL 389
              ...| ||.::||   :.:..|.||.:..: |:.|..:|
Human   359 --NAASFKEVSDSL---LTSSKGQLQKMKES-LDDVMDYL 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lsd-1	NP_732904.2	Perilipin	14..>295	CDD:281086	67/329 (20%)
PLIN2	XP_016869748.1	Perilipin	6..395	CDD:281086	89/430 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CMU0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437332at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14024
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4632
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950