DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PTPMT1 and F28C6.8

DIOPT Version :9

Sequence 1:	NP_651180.3	Gene:	PTPMT1 / 42807	FlyBaseID:	FBgn0039111	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_001254161.1	Gene:	F28C6.8 / 174381	WormBaseID:	WBGene00009207	Length:	189	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	72/206 - (34%)
Similarity:	103/206 - (50%)	Gaps:	31/206 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MFARVSFYPTLLYNVLMEKASARN--WYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMNEDY 69
            |...:.|||:|.||:.........  ||:|:||.:||||:||||..::||:|||:..||...|::
Worm     1 MLTSLIFYPSLGYNLFRNYVQPNRWAWYNRVDETLILGAMPFRSMKDELIQKENVGGVVCCTEEF 65

  Fly    70 ELTAFSNNTEK--WRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLKQRIGGLSSSYQPE 132
            ||.|..|...:  |:..|:||..:...|...:..:.::...||||                   |
Worm    66 ELKAAMNAMREVDWKNEGVEFFAVPMKDFTGTAPRAEINEAVEFI-------------------E 111

  Fly   133 NVGS----VYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDAL----R 189
            :|.|    ||||||||||||||:..||||....|..:.|.:.::..|..:||....|..:    |
Worm   112 SVASKGKTVYVHCKAGRTRSATVATCYLMKSRNWMSNVAWEFLKDKRHQVLLRNAHWRTVNEYRR 176

  Fly   190 LFYTNNVETKS 200
            ...:|:..|.|
Worm   177 FLDSNSSSTGS 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PTPMT1	NP_651180.3	PTPMT1	31..194	CDD:350374	62/172 (36%)
F28C6.8	NP_001254161.1	DSPc	49..175	CDD:279164	48/144 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159211
Domainoid	1	1.000	66	1.000	Domainoid score	I6568
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11973
Inparanoid	1	1.050	116	1.000	Inparanoid score	I3389
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48913
OrthoDB	1	1.010	-	-		D1386941at2759
OrthoFinder	1	1.000	-	-		FOG0005731
OrthoInspector	1	1.000	-	-		oto19776
orthoMCL	1	0.900	-	-		OOG6_104823
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3413
SonicParanoid	1	1.000	-	-		X4126
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.800