DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PTPMT1 and PTPMT1

DIOPT Version :9

Sequence 1:	NP_651180.3	Gene:	PTPMT1 / 42807	FlyBaseID:	FBgn0039111	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_783859.1	Gene:	PTPMT1 / 114971	HGNCID:	26965	Length:	201	Species:	Homo sapiens

Alignment Length:	190	Identity:	79/190 - (41%)
Similarity:	116/190 - (61%)	Gaps:	18/190 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AMFARVSFYPTLLYNVLMEKA---SARNWYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMNE 67
            |..|||.|||||||.:...|.   :.|:||.|||..|:|||||.||....|::.||::.|::|||
Human     9 AGLARVLFYPTLLYTLFRGKVPGRAHRDWYHRIDPTVLLGALPLRSLTRQLVQDENVRGVITMNE 73

  Fly    68 DYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLKQRIGGLSSSYQPE 132
            :||.....|::::|::||:|.|:|:|.|:...|..:.|.:||:|..|:..|.|
Human    74 EYETRFLCNSSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQSLGQ------------ 126

  Fly   133 NVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY 192
               .|||||||||:||||:|..||:..:.|:|::||..:.|.|.:|.:...|.|.|:.|:
Human   127 ---CVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAIAKIRSYIHIRPGQLDVLKEFH 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PTPMT1	NP_651180.3	PTPMT1	31..194	CDD:350374	66/162 (41%)
PTPMT1	NP_783859.1	PTPc	40..182	CDD:304379	56/141 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147033
Domainoid	1	1.000	96	1.000	Domainoid score	I7400
eggNOG	1	0.900	-	-		E1_KOG1719
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11973
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4387
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48913
OrthoDB	1	1.010	-	-		D1386941at2759
OrthoFinder	1	1.000	-	-		FOG0005731
OrthoInspector	1	1.000	-	-		oto91234
orthoMCL	1	0.900	-	-		OOG6_104823
Panther	1	1.100	-	-	LDO	PTHR46712
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3413
SonicParanoid	1	1.000	-	-		X4126
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800