Protein Alignment Rpt5 and YTA12

DIOPT Version :10

• Sequence 1: NP_524464.1
• Gene: Rpt5 / 42805
• FlyBaseID: FBgn0028684
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_013807.1
• Gene: YTA12 / 855114
• SGDID: S000004695
• Length: 825
• Species: Saccharomyces cerevisiae
• Alignment Length: 544
• Identity: 144/544 - (26%)
• Similarity: 227/544 - (41%)
• Gaps: 165/544 - (30%)

  Fly    11 WEDGEESLGEEVMRMSTDEIVSRTRLMDNEIKIMKSEVIRITHEIQAQNEKIKDN-TEKIKVNKT 74
            |::.:..:.|.:.|:              |..::|.|..||..|   :.||.::| ..|.|.|:|
Yeast    93 WKEQKRKIDESIRRL--------------EDAVLKQESNRIQEE---RKEKEEENGPSKAKSNRT 140

  Fly    75 -------------LP--------------------------------YLVSNVIELLDVDPQEEE 94
                         :|                                :|:|.:::||:    ..|
Yeast   141 KEQGYFEGNNSRNIPPPPPPPPPKPPLNDPSNPVSKNVNLFQIGLTFFLLSFLLDLLN----SLE 201

  Fly    95 DDGSVTVLDNQRK-------GKCAVIKTST-----------------RQAYFLPVIGLVDA--EK 133
            :...:|..|.:.|       .|..|:..|.                 |..|:. .||.:|:  .|
Yeast   202 EQSEITWQDFREKLLAKGYVAKLIVVNKSMVKVMLNDNGKNQADNYGRNFYYF-TIGSIDSFEHK 265

  Fly   134 L-KPGDLVGVNKD----------------SYLILETL---------------------------- 153
            | |..|.:.::||                .:.||.|:
Yeast   266 LQKAQDELDIDKDFRIPVLYVQEGNWAKAMFQILPTVLMIAGIIWLTRRSAQAAGGSRGGIFGLS 330

  Fly   154 -------PAEYDARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKG 211
                   ..|.|.::|           :.|:.|.|:..:|::|.|.. :....:::.:|...|:|
Yeast   331 RSKAKKFNTETDVKIK-----------FKDVAGCDEAKEEIMEFVSF-LKEPSRYEKMGAKIPRG 383

  Fly   212 VLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDE 276
            .:|.|||||||||||:|.|.:....|..::|.:.|:||:|.||..|||.|..|:|.||:|:||||
Yeast   384 AILSGPPGTGKTLLAKATAGEAGVPFYFVSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDE 448

  Fly   277 LDAIGTKRFDSEKAG-DREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLDRK 340
            :||||..|.....:| :.|.:.|:.::|.::|||:....:.|:|.|||.||||.||||.||.||.
Yeast   449 IDAIGKARQKGNFSGANDERENTLNQMLVEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRH 513

  Fly   341 IEFPHPNEEARARIMQIHSRKMNVSNDVNFE---ELSRSTDDFNGAQCKAVCVEAGMIALRRSAN 402
            |....|..|.|..|..:|...:.::.:: |:   .|:..|..|:||....||.||.:||.|...:
Yeast   514 INIDKPELEGRKAIFAVHLHHLKLAGEI-FDLKNRLAALTPGFSGADIANVCNEAALIAARSDED 577

  Fly   403 SVTHEDFMDAIMEV--QAKKKANL 424
            :|....|..||..|  ..::|:.|
Yeast   578 AVKLNHFEQAIERVIGGVERKSKL 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt5	NP_524464.1	PRK03992	28..421	CDD:179699	139/522 (27%)
YTA12	NP_013807.1	FtsH_ext	<205..282	CDD:377663	17/77 (22%)
		FtsH_fam	290..784	CDD:273520	105/325 (32%)