DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt5 and psmc1a

DIOPT Version :9

Sequence 1:	NP_524464.1	Gene:	Rpt5 / 42805	FlyBaseID:	FBgn0028684	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_956327.1	Gene:	psmc1a / 336786	ZFINID:	ZDB-GENE-030131-8730	Length:	440	Species:	Danio rerio

Alignment Length:	398	Identity:	183/398 - (45%)
Similarity:	260/398 - (65%)	Gaps:	32/398 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RTRLMDNE-IK---IMKSEVIRITHEIQAQNEKIKDNTEKIKVNKTLPYLVSNVIELLDVDPQEE 93
            |.:|:..| ||   :|:.|.||...:::...||.::...|:...:..|..|..:.|::|
Zfish    59 RLKLLKQERIKDYLLMEEEFIRDQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIID------ 117

  Fly    94 EDDGSVTVLDNQRKGKCAVIKTSTRQAYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPAEYD 158
                     ||.     |::.||....:::.::..||.:.|:||..|.:|...:.::..|..:.|
Zfish   118 ---------DNH-----AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTD 168

  Fly   159 ARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPPGTGKT 223
            ..|..|:|::.|.|.|:||||||.||||:.|:|.||:||.|.::.:||.|||||:|||.||||||
Zfish   169 PLVTVMKVEKAPQETYADIGGLDSQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGAPGTGKT 233

  Fly   224 LLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSE 288
            |||:|.|.||.:|||::.|.:|:|.::|||.||||:.|.:|:|.||:|:||||:|||||||:||.
Zfish   234 LLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSN 298

  Fly   289 KAGDREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARAR 353
            ..|:||:||||||||||||||.|..|:|||.||||::.|||||:|.||:|||||||.|:|:.:.|
Zfish   299 SGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRR 363

  Fly   354 IMQIHSRKMNVSNDVNFEELSRSTDDFNGAQCKAVCVEAGMIALRRSANSVTHEDFMDAIMEVQA 418
            |.|||:.:|.|::||..::|..:.||.:||..||:|.|||::|||.....||:|||        .
Zfish   364 IFQIHTSRMTVADDVTLDDLILAKDDLSGADIKAICTEAGLMALRERRMKVTNEDF--------K 420

  Fly   419 KKKANLNY 426
            |.|.|:.|
Zfish   421 KSKENVLY 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt5	NP_524464.1	RPT1	33..421	CDD:224143	180/391 (46%)
psmc1a	NP_956327.1	PTZ00361	25..440	CDD:185575	183/398 (46%)
		Prot_ATP_ID_OB	108..>176	CDD:293059	19/87 (22%)
		AAA	222..355	CDD:278434	89/132 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920