DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpt5 and Psmc1

DIOPT Version :9

Sequence 1:	NP_524464.1	Gene:	Rpt5 / 42805	FlyBaseID:	FBgn0028684	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_476464.1	Gene:	Psmc1 / 117263	RGDID:	621097	Length:	440	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	183/398 - (45%)
Similarity:	261/398 - (65%)	Gaps:	32/398 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RTRLMDNE-IK---IMKSEVIRITHEIQAQNEKIKDNTEKIKVNKTLPYLVSNVIELLDVDPQEE 93
            |.:|:..| ||   :|:.|.||...:::...||.::...|:...:..|..|..:.|::|
  Rat    59 RLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIID------ 117

  Fly    94 EDDGSVTVLDNQRKGKCAVIKTSTRQAYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPAEYD 158
                     ||.     |::.||....:::.::..||.:.|:||..|.:|...:.::..|..:.|
  Rat   118 ---------DNH-----AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTD 168

  Fly   159 ARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPPGTGKT 223
            ..|..|:|::.|.|.|:||||||.||||:.|:|.||:||.|.::.:||.|||||:||||||||||
  Rat   169 PLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKT 233

  Fly   224 LLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSE 288
            |||:|.|.||.:|||::.|.:|:|.::|||.||||:.|.:|:|.||:|:||||:|||||||:||.
  Rat   234 LLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSN 298

  Fly   289 KAGDREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARAR 353
            ..|:||:||||||||||||||.|..|:|||.||||::.|||||:|.||:|||||||.|:|:.:.|
  Rat   299 SGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363

  Fly   354 IMQIHSRKMNVSNDVNFEELSRSTDDFNGAQCKAVCVEAGMIALRRSANSVTHEDFMDAIMEVQA 418
            |.|||:.:|.:::||..::|..:.||.:||..||:|.|||::|||.....||:|||        .
  Rat   364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDF--------K 420

  Fly   419 KKKANLNY 426
            |.|.|:.|
  Rat   421 KSKENVLY 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt5	NP_524464.1	RPT1	33..421	CDD:224143	180/391 (46%)
Psmc1	NP_476464.1	PTZ00361	1..440	CDD:185575	183/398 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..104		3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920