Protein Alignment Rpt5 and AFG3L2

DIOPT Version :10

• Sequence 1: NP_524464.1
• Gene: Rpt5 / 42805
• FlyBaseID: FBgn0028684
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_006787.2
• Gene: AFG3L2 / 10939
• HGNCID: 315
• Length: 797
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 108/287 - (37%)
• Similarity: 172/287 - (59%)
• Gaps: 20/287 - (6%)

  Fly   156 EYDARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLYGPPGT 220
            |..|:|...|:|.:    :.|:.|.::...|::|.|.. :.:.:::::||...|||.:|.|||||
Human   293 ETTAKVLKDEIDVK----FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGT 352

  Fly   221 GKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRF 285
            ||||||:|.|.:....|:.::|.:.::||:|.|...|||.||||::.||.|:||||:||:|.||.
Human   353 GKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRG 417

  Fly   286 DSEKAGDREVQRTMLELLNQLDGFSSTADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEA 350
            .....|..|.:.|:.:||.::|||::|.::.::|.|||.|||||||||.||.||:|....|:.:.
Human   418 RGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482

  Fly   351 RARIMQIHSRKMNVSNDVNFEELSRS----TDDFNGAQCKAVCVEAGMIALRRSANSVTHEDFMD 411
            ||.|.::|.|.:.:.:.:..::|:|.    |..|:||....||.||.:||.|..::|:..:.|..
Human   483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHFEQ 547

  Fly   412 AIMEV-----------QAKKKANLNYY 427
            ||..|           |.::|..:.|:
Human   548 AIERVIGGLEKKTQVLQPEEKKTVAYH 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt5	NP_524464.1	PRK03992	28..421	CDD:179699	106/279 (38%)
AFG3L2	NP_006787.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..126
		HflB	151..747	CDD:440233	108/287 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..797