DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RanBP3 and Ranbp3

DIOPT Version :9

Sequence 1:	NP_651178.1	Gene:	RanBP3 / 42804	FlyBaseID:	FBgn0039110	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_006244419.1	Gene:	Ranbp3 / 501281	RGDID:	1589604	Length:	567	Species:	Rattus norvegicus

Alignment Length:	472	Identity:	147/472 - (31%)
Similarity:	200/472 - (42%)	Gaps:	125/472 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GFTLKASRL--GGA----------------VLRPAVL--------------------ANSSGSNN 43
            ||.||...|  |.|                |||||||                    ..|||:|.
  Rat   135 GFRLKPPTLIHGQAPSAGLPSQKPREQQRGVLRPAVLQAPQPKVLSQTGVLLLSTLEVPSSGTNG 199

  Fly    44 SS-----TSP--SAGEDSALLNNPFLRESKDDDDDEEVVATGSAAAESTGDKEDDDVDERPDPLT 101
            .|     |.|  ||..::....:|                  |.:||.|...|:....:.|
  Rat   200 VSMPADCTGPATSASPENLTQRSP------------------SESAEGTHTFEEKVPQKTP---- 242

  Fly   102 KLRSNGIERSSMFAAAKNNMPNVQSSGFVFGQNVHERVVAPNAEQVTAEPDADTAASSVS----- 161
               |.|.|.:..      ....|....||||||:.:||...|.:...|  |.|:||...|
  Rat   243 ---SGGSEETHC------EEEQVAPQAFVFGQNLRDRVKLMNEKANVA--DVDSAAHPGSETPTA 296

  Fly   162 -------AQEAASSSTAATSSSAPLLFSSVIQNAAQ-----------TTETSEAAASSSICSSSS 208
                   ...:|.:||.:..:|...:|.   ||.::           .::||.....:...|.||
  Rat   297 TNYFLQYISSSADNSTHSADTSTKFVFG---QNMSERVLSPPKLNEANSDTSRETTHAQSGSESS 358

  Fly   209 NNKESAEAKSLTDVAREYEESRAQKRKYEEVETFTGEEDEINIIDVSCKLFAF--LNSNWEERGR 271
            :.:...:.:||.:.|..|.::.|.....|:||..||||.|.|::.:.||||.|  .:.:|.||||
  Rat   359 SQEAVPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGR 423

  Fly   272 GSLRLND---AKDLRGDSRVVFRTSGNLRLLLNTKVWAAMVAERASQKSLRLTAID--NSGVVKI 331
            |.|||||   |.|....||:|.||.|:|||:||||:||.|..::||:||:|:||.|  :.| ||:
  Rat   424 GLLRLNDMASADDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITATDAEDQG-VKV 487

  Fly   332 FLAMGRPADIAQLHKALSERIAKRKVSHPEECSVEEAKNGVASEAAASLQPEST---THDDEDED 393
            ||......|..||:.||..||...:....:|   :|||       |...:|.:|   ..:|.|||
  Rat   488 FLISASSKDTGQLYAALHHRILALRSRAEQE---QEAK-------APPPEPGATRAAEEEDSDED 542

  Fly   394 AAPGPSGAISAEADSYG 410
            |...|||...|.|...|
  Rat   543 AVLAPSGVTGAGAGDDG 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RanBP3	NP_651178.1	RanBD_RanBP3	243..352	CDD:270001	58/115 (50%)
Ranbp3	XP_006244419.1	RanBD_RanBP3	393..508	CDD:270001	58/115 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8742
eggNOG	1	0.900	-	-		E1_KOG0866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4216
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001968
OrthoInspector	1	1.000	-	-		otm45696
orthoMCL	1	0.900	-	-		OOG6_107245
Panther	1	1.100	-	-	LDO	PTHR23138
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860