Protein Alignment RanBP3 and Nup358

DIOPT Version :10

• Sequence 1: NP_651178.1
• Gene: RanBP3 / 42804
• FlyBaseID: FBgn0039110
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001247302.1
• Gene: Nup358 / 43041
• FlyBaseID: FBgn0039302
• Length: 2718
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 105/458 - (22%)
• Similarity: 166/458 - (36%)
• Gaps: 105/458 - (22%)

  Fly    19 TLKASRLGGAVLRPAVLANSSGSNNSSTSPSAGE--------------DSALLNNPFLRESKDDD 69
            |..|..:.|.|..||..|.....:....:||...              :.||.|.|..:|
  Fly  1127 TAPAPPIAGTVNPPATTAVPPPVHIPQVAPSVPAQPPAPAPVSVPSMFNRALNNQPVEKE----- 1186

  Fly    70 DDEEVVATGSAAAESTGDKEDDDVDERPDPLTKLRSNGIERS-SMFAAAKNNMPNVQSSGFVFGQ 133
            ....||.|.|                  |||.|..:..::.: |:...|::..|::
  Fly  1187 PPANVVITSS------------------DPLPKPTTASVQPTLSVTIPAQHIKPSL--------- 1224

  Fly   134 NVHERVVAPNAEQVTAEPDADTAASSVSAQEAASSSTAATSSSAPLLFSSVIQNAAQTTETSEAA 198
                 |.||.....:|:|    |..|||...:.|.:..:.||.:|..|.:.:..||...:..:..
  Fly  1225 -----VQAPEQPAQSAQP----AQPSVSGVGSLSFNFGSKSSESPFSFKTQVAKAAAEKQKEQEE 1280

  Fly   199 ASSSICSSSSNNKESAEAKSLTDVAREYEESRAQKRKY----EEVETFTGEEDEINIIDVSCKLF 259
            |..:...::..||...:..|..|.     :.|...:..    :|||..||||.|........|||
  Fly  1281 AEQNQSGATDPNKTLPQDTSADDY-----DPRPDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLF 1340

  Fly   260 AFLNSNWEERGRGSLRLNDAKDLRGDSRVVFRTSGNLRLLLNTKVWAAMVAERASQ----KSLRL 320
            .:::..|:|||.|.:::...| ..|.|||:.|.....::..|..:.|.:....|:|    |||..
  Fly  1341 RYVDKEWKERGTGVIKILCDK-ATGVSRVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLW 1404

  Fly   321 TA---IDNSGVVKIFLAMGRPADIAQLHK---------ALSERIAKRKVSHPEECSVEEA----K 369
            .|   .|....::.||...:..::|:..:         |.|:...|..|:..|:.|...|    |
  Fly  1405 AANDFADEQVTLERFLVRFKTGELAEEFRVAFTKASEAAKSKETVKPTVNTAEKGSTATAPAAFK 1469

  Fly   370 NGVASEAAASL-----QPESTTHDDEDEDAAPGPS--GAISAEADSYGPSPKKVIVQPDSSADVP 427
            :.|.|..||:.     |.::.|..:.|..|....|  |.:|..|            .|.:||...
  Fly  1470 SFVTSTPAANSLINKPQEQTKTQPNPDPPATAAKSLFGTLSVSA------------APATSAPAS 1522

  Fly   428 VPP 430
            ..|
  Fly  1523 ATP 1525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RanBP3	NP_651178.1	RanBD_RanBP3	243..352	CDD:270001	33/124 (27%)
Nup358	NP_001247302.1	LapB	<30..204	CDD:442196
		TPR repeat	58..90	CDD:276809
		PHA03247	<1030..1308	CDD:223021	46/226 (20%)
		RanBD1_RanBP2_insect-like	1324..1442	CDD:269992	31/118 (26%)
		RanBD2_RanBP2_insect-like	1620..1737	CDD:269993
		ZnF_RBZ	1772..1796	CDD:197784
		RanBP2-type Zn finger	1774..1793	CDD:275376
		Nucleoporin_FG2	1806..>1985	CDD:435043
		RanBP2-type Zn finger	1833..1861	CDD:275375
		zf-RanBP	1891..1917	CDD:395516
		RanBP2-type Zn finger	1894..1913	CDD:275376
		RanBD3_RanBP2_insect-like	2034..2148	CDD:269994
		RanBD4_RanBP2_insect-like	2571..2694	CDD:269995