Protein Alignment RanBP3 and RANBP3L

DIOPT Version :9

• Sequence 1: NP_651178.1
• Gene: RanBP3 / 42804
• FlyBaseID: FBgn0039110
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_006714515.1
• Gene: RANBP3L / 202151
• HGNCID: 26353
• Length: 519
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 107/391 - (27%)
• Similarity: 165/391 - (42%)
• Gaps: 97/391 - (24%)

  Fly    29 VLRPAVLANSSGSNNSSTSPSAGEDSALLNNPFLRESKDDDDDEEVVATGSAAAES--TGDKEDD 91
            |:|||:|          ..|.| ...|.:...|                |..|.||  |.:|.::
Human   147 VIRPAIL----------QLPQA-RSCAKVRKTF----------------GHKALESCKTKEKTNN 184

  Fly    92 DVDERPDPLTKLRSNGIERSSMFAAAKNN-----------MPNVQ-------SSGFVFGQNVHER 138
            .:.|..   :.|.|..:.|:.:......|           .||..       ||.||||:|:.||
Human   185 KISEGN---SYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVER 246

  Fly   139 VVAPNAEQVTAEPDADTAASSVSAQEAASSSTAATSSSAPLLFSSVIQNAAQTTETSEAAASSSI 203
            |:   ..|...:|.                                ::|.:...|....:.....
Human   247 VL---GTQKLTQPQ--------------------------------LENDSYAKEKPFKSIPKFP 276

  Fly   204 CSSSSNNKESAEAKSLTDVAREYEESRAQKRKYEEVETFTGEEDEINIIDVSCKLFAF--LNSNW 266
            .:..|:..:|.:..||.:.|..:....::|...|:::..||||.|.|::.::||||.|  ...:|
Human   277 VNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSW 341

  Fly   267 EERGRGSLRLNDAKDL---RGDSRVVFRTSGNLRLLLNTKVWAAMVAERASQKSLRLTAID-NSG 327
            .|||||:|||||....   ...||::.|..|:|||:||:|:||.|..:||:.|::|:||.| ...
Human   342 IERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDY 406

  Fly   328 VVKIFLAMGRPADIAQLHKALSERIAKRKVSHPEECSVEEAKNGVASEAAASLQPESTTHDDEDE 392
            .:||||......|.|.|:.|:..|:...: |..::..|.:|::  .||.|..|..||.   ||:|
Human   407 SIKIFLIQASAQDTAYLYAAIHHRLVALQ-SFNKQRDVNQAES--LSETAQQLNCESC---DENE 465

  Fly   393 D 393
            |
Human   466 D 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RanBP3	NP_651178.1	RanBD_RanBP3	243..352	CDD:270001	50/114 (44%)
RANBP3L	XP_006714515.1	RanBD_RanBP3	316..431	CDD:270001	50/114 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9167
eggNOG	1	0.900	-	-		E1_KOG0866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4189
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001968
OrthoInspector	1	1.000	-	-		otm41572
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23138
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3882
SonicParanoid	1	1.000	-	-		X7579
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.950