Protein Alignment RanBP3 and RanBP3

DIOPT Version :10

• Sequence 1: NP_651178.1
• Gene: RanBP3 / 42804
• FlyBaseID: FBgn0039110
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_313820.5
• Gene: RanBP3 / 1274666
• VectorBaseID: AGAMI1_002667
• Length: 490
• Species: Anopheles gambiae
• Alignment Length: 499
• Identity: 191/499 - (38%)
• Similarity: 260/499 - (52%)
• Gaps: 95/499 - (19%)

  Fly     1 MSENNEASVETNCFRG--------GFTLKASRL-----GGAVLRPAVLANSSGSNNSSTSPS--- 49
            ::|..|:| ::|...|        .|.||:|.|     ||:.....  ..||.||:.|:|||
Mosquito    11 LNEEQESS-QSNSSNGSSSVVQPSSFQLKSSVLRQSTFGGSAFLGG--GGSSSSNSISSSPSLAG 72

  Fly    50 -AGEDSALLN-------------------------------------------NPFLRESKDDDD 70
             ||.::.|.|                                           ||||:....:|:
Mosquito    73 FAGGNAGLANSFNLKPSVLKPSQLSFGGIGSIKEGNGAAADKNGNDAVAPAPTNPFLKTQFSEDE 137

  Fly    71 DEEVVATGSAA--AESTGDKEDDDV--DERPDPLTKLRSNGIERSSMFAAAKNNMPNVQSSGFVF 131
            ..:..|.|.:|  ::|..||:.|:.  ....|||.||:|..:.:|::||..|.:..:..|.||||
Mosquito   138 PSDADAKGGSAESSKSATDKDGDNSTNSNNIDPLAKLKSASLPKSNLFANVKKSTLSEASCGFVF 202

  Fly   132 GQNVHERVVAPNAEQVTAEPDADTA---ASSVSAQEAASSSTAATSSSAPLLFSSVIQNAAQTTE 193
            ||||||||...|....:|.....|.   |:||:|....|.:..|..::|         |.|.:..
Mosquito   203 GQNVHERVTGENLSNASANTLPTTGFSFATSVAATAGESGTGGAGGNTA---------NTASSNA 258

  Fly   194 TSEAAASSSICSSSSNNKESAEAKSLTDVAREYEESR-AQKRKYEEVETFTGEEDEINIIDVSCK 257
            :..|.......||..:::|..:.:||.:.||.||||| |.|||||||||.||||||.|:::::||
Mosquito   259 SGTATGKDGSDSSDGSSREPKDRESLEEAARRYEESRGALKRKYEEVETITGEEDERNVVEINCK 323

  Fly   258 LFAFLNSNWEERGRGSLRLNDAKDLRGDSRVVFRTSGNLRLLLNTKVWAAMVAERASQKSLRLTA 322
            ||||..|||||||.|:||||| || ..:||||||.|||||:|:||||||.|||::.|||||||||
Mosquito   324 LFAFAKSNWEERGHGTLRLND-KD-NNESRVVFRQSGNLRVLINTKVWAGMVAQQPSQKSLRLTA 386

  Fly   323 IDNSGVVKIFLAMGRPADIAQLHKALSERIAKRKVSHPEECSVEEAKNGVASEAAASLQPESTTH 387
            ||::|.:|:||.|.||..|.:|||.||:||...|.:..:|.:.|   |...::.|..:.|.|.
Mosquito   387 IDSTGQIKVFLVMSRPEVITKLHKELSKRIETAKQTAEQEAAKE---NKDDNKPAVPIAPSSL-- 446

  Fly   388 DD---EDEDAAPGPSGA---ISAEADSYGPSPKK--VIVQPDSS 423
            ||   :|..:.|.|:..   :|...|:..||.||  .|..|.||
Mosquito   447 DDAGSDDGSSIPVPADTEHLLSNADDADEPSSKKRASITSPPSS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RanBP3	NP_651178.1	RanBD_RanBP3	243..352	CDD:270001	73/108 (68%)
RanBP3	XP_313820.5	RanBD_RanBP3	309..416	CDD:270001	49/112 (44%)