DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn9 and Psmd13

DIOPT Version :9

Sequence 1:	NP_651177.1	Gene:	Rpn9 / 42802	FlyBaseID:	FBgn0028691	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_036005.1	Gene:	Psmd13 / 23997	MGIID:	1345192	Length:	376	Species:	Mus musculus

Alignment Length:	376	Identity:	172/376 - (45%)
Similarity:	256/376 - (68%)	Gaps:	3/376 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NVTAYLATQKKTTNKELAAEWTLIEELYNEKLWNELTIKLVTFVRHESLQDETALLQLYQNFLST 71
            :|.|:| .|.:::....||.|..:||||.:|||::||::::.||:.........|::||:||:|.
Mouse     3 DVPAFL-QQSQSSGPGQAAVWHRLEELYTKKLWHQLTLEVLDFVQDPCFAQGDGLIKLYENFISE 66

  Fly    72 FETKINPYGLIQILEVVVDNIGDKKEAIEFLEKMKDKVKICDEAVWYLQVMQGNLYLSNLNDLNA 136
            ||.::||..|::|:..||..:.|...|:.||||.::|||..||||...:...|.|.| |:.||.|
Mouse    67 FEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKL-NIGDLQA 130

  Fly   137 TKKIIEELRDVLEEAGNVTPVHGKYYMLASQYYRRVGKHSDYYRCGLQFLGC-SMDEYPRDQWAQ 200
            ||:.||::.::|.....||.||.::|.|:|:||:.:|.|:.||:..|:|||| .:.:.|..:..:
Mouse   131 TKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQE 195

  Fly   201 QAFFLGLAALLGDGVYNIGELLAHPILESLKGTENEWLMELLKAFNTGDINKFNDMKKIWSKIPD 265
            :||.||||.|||:||:|.||||.||:||||:.|:.:||::.|.|||:|.:::|..:|..|.:.||
Mouse   196 RAFTLGLAGLLGEGVFNFGELLMHPVLESLRDTDRQWLIDTLYAFNSGAVDRFQTLKCAWGQQPD 260

  Fly   266 LAAQEVKLRQKISLLCLMEMTFKRSAIERAISFTDIAQETKLPAKEVELLIMKALALDLVRGEID 330
            |||.|.:|.:||.|||||||||.|.|..|.::|.:||:..|:...:||||:||||::.||||.||
Mouse   261 LAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNKVELLVMKALSVGLVRGSID 325

  Fly   331 QVAGVVNMSWVQPRVLNRSQIVGMASTLDTWMGAITNMEKLMENRAAEILT 381
            :|...|:|:|||||||:..||.||...|:.|...:.:||.|:|::|.:|||
Mouse   326 EVDKRVHMTWVQPRVLDLQQIKGMKDRLELWCTDVKSMEMLVEHQAQDILT 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn9	NP_651177.1	PAM	269..361	CDD:214803	49/91 (54%)
Psmd13	NP_036005.1	PCI	231..335	CDD:279707	52/103 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836859
Domainoid	1	1.000	194	1.000	Domainoid score	I3171
eggNOG	1	0.900	-	-		E1_KOG2908
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2110
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2372
Isobase	1	0.950	-	0	Normalized mean entropy	S1269
OMA	1	1.010	-	-		QHG54044
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004223
OrthoInspector	1	1.000	-	-		oto92354
orthoMCL	1	0.900	-	-		OOG6_101776
Panther	1	1.100	-	-	LDO	PTHR10539
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1208
SonicParanoid	1	1.000	-	-		X2969
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740