DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn9 and rpn-9

DIOPT Version :9

Sequence 1:	NP_651177.1	Gene:	Rpn9 / 42802	FlyBaseID:	FBgn0028691	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_496405.1	Gene:	rpn-9 / 174715	WormBaseID:	WBGene00004465	Length:	387	Species:	Caenorhabditis elegans

Alignment Length:	385	Identity:	142/385 - (36%)
Similarity:	224/385 - (58%)	Gaps:	19/385 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YLATQKKTTNKELAAEWTLIEELYNEKLWNELTIKLVTFVRHESLQDETALLQLYQNFLSTFETK 75
            ||..:....|..||.:|..::||:.:|||::||:...:.|:.......|.:.:.|:.|::.:|.:
Worm     6 YLNGKLAAANGPLADDWKNLKELWEKKLWHQLTVLTRSLVKKPQFVASTDMHEFYRLFVAEWELR 70

  Fly    76 INPYGLIQILEVVVDNIG--DKKEAIEFLEKM-----KDKVKICDEAVWYLQVMQGNLYLSN--- 130
            :||..|::|...:..||.  ||::::|||.|:     |||:     ||..|...:....|.|
Worm    71 VNPLQLVEICISIAQNIATKDKQKSMEFLSKIGNVINKDKI-----AVARLHTGEIEARLENKDK 130

  Fly   131 ---LNDLNATKKIIEELRDVLEEAGNVTPVHGKYYMLASQYYRRVGKHSDYYRCGLQFLGC-SMD 191
               :.||.:.:..|:..:..::....||.||..:|.::|.|.|.||..:.|||..|::||. ..:
Worm   131 NGQIIDLKSIRTQIDSTQHEVDSLVGVTEVHAPFYRVSSLYLREVGDFAGYYREALRYLGVEDAN 195

  Fly   192 EYPRDQWAQQAFFLGLAALLGDGVYNIGELLAHPILESLKGTENEWLMELLKAFNTGDINKFNDM 256
            ....:|....|..||.|||||:.|:|.|||||||||:||:||...|::::|.|||:||:.:|..:
Worm   196 NLTTEQKQVHAVLLGFAALLGENVHNFGELLAHPILKSLEGTRERWIVDVLLAFNSGDLTRFFSL 260

  Fly   257 KKIWSKIPDLAAQEVKLRQKISLLCLMEMTFKRSAIERAISFTDIAQETKLPAKEVELLIMKALA 321
            :..|....||..|:..|..||.|:.:||:...|....|::||.:||.:.::|..|||.|:||||:
Worm   261 EGDWGGWDDLKKQKDFLTAKIRLMAVMELAVSRPTKARSVSFKEIATKCQIPFDEVEFLVMKALS 325

  Fly   322 LDLVRGEIDQVAGVVNMSWVQPRVLNRSQIVGMASTLDTWMGAITNMEKLMENRAAEILT 381
            .||:||:|:||..||.::|||||||:..||:.||:.:..|...:.:||.::...|.||||
Worm   326 KDLIRGDINQVEQVVYVTWVQPRVLDNPQIMQMATRISAWRNDVNSMEGIVSKEAREILT 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn9	NP_651177.1	PAM	269..361	CDD:214803	42/91 (46%)
rpn-9	NP_496405.1	PAM	272..365	CDD:214803	42/92 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159125
Domainoid	1	1.000	129	1.000	Domainoid score	I3263
eggNOG	1	0.900	-	-		E1_KOG2908
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2110
Inparanoid	1	1.050	250	1.000	Inparanoid score	I2001
Isobase	1	0.950	-	0	Normalized mean entropy	S1269
OMA	1	1.010	-	-		QHG54044
OrthoDB	1	1.010	-	-		D379636at33208
OrthoFinder	1	1.000	-	-		FOG0004223
OrthoInspector	1	1.000	-	-		oto17554
orthoMCL	1	0.900	-	-		OOG6_101776
Panther	1	1.100	-	-	LDO	PTHR10539
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1208
SonicParanoid	1	1.000	-	-		X2969
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790