Protein Alignment CG10232 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 101/362 - (27%)
• Similarity: 152/362 - (41%)
• Gaps: 104/362 - (28%)

  Fly   191 DEKCIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNV------------ 243
            |...:|.|..::...|...:||::..         ||:|..|..:  ...||:
Human   108 DGSGVRADVVMKFQFTRNNNGASMKS---------RIESVLRQML--NNSGNLEINPSTEITSLT 161

  Fly   244 -------LPTSCGQAPPL-----YRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKR 296
                   |...||..|.|     .|:..||.|....:||...|...|      .::|.|||||..
Human   162 DQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNN------AHHCGGSLINNM 220

  Fly   297 YVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNP-DCDFTGNCAAPFVEIGIEYFN--VHEQYF 358
            ::||||||...:                    :|| |...|...:..|.::.:...|  :|..|
Human   221 WILTAAHCFRSN--------------------SNPRDWIATSGISTTFPKLRMRVRNILIHNNY- 264

  Fly   359 NTSRFESDIALVRLQTPVRYTHEILPICVPKDPIPLHNHP----LQIAGWGYTKNREYSQVLLHN 419
            .::..|:|||||||:..|.:|.:|..:|:   |....|.|    ..:.|||   .:||:    .:
Human   265 KSATHENDIALVRLENSVTFTKDIHSVCL---PAATQNIPPGSTAYVTGWG---AQEYA----GH 319

  Fly   420 TVYENRYYCQDKISFFRNE--------------SQICASGI--RGEDSCEGDSGGPLMLTLNNDY 468
            ||.|.|   |.::....|:              ..:|| |:  .|.|:|:|||||||   :..|.
Human   320 TVPELR---QGQVRIISNDVCNAPHSYNGAILSGMLCA-GVPQGGVDACQGDSGGPL---VQEDS 377

  Fly   469 QDIVYLAGIVSYGSENCG-DRKPGVYTKTGAFFSWIK 504
            :.:.::.||||:| :.|| ..||||||:..|:..||:
Human   378 RRLWFIVGIVSWG-DQCGLPDKPGVYTRVTAYLDWIR 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	83/269 (31%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	10/48 (21%)
		Tryp_SPc	187..415	CDD:238113	83/272 (31%)