Protein Alignment CG10232 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 84/326 - (25%)
• Similarity: 132/326 - (40%)
• Gaps: 63/326 - (19%)

  Fly   207 TMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLP-------------------TSCGQAP 252
            |...|.||.|        .:::|.:......|..|..|.                   :.||..|
Human   157 THHKGVNLTD--------IKLNSSQEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARP 213

  Fly   253 PLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVL 317
            ...|:..|.:..|..:||.|.:....|      :.|.||::..|:|:|||||:...::..  |..
Human   214 LASRIVGGQSVAPGRWPWQASVALGFR------HTCGGSVLAPRWVVTAAHCMHSFRLAR--LSS 270

  Fly   318 RRVRLG--EHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRYTH 380
            .||..|  .|            :...|.....:|....|..| :....:.|:||:||||.:.::.
Human   271 WRVHAGLVSH------------SAVRPHQGALVERIIPHPLY-SAQNHDYDVALLRLQTALNFSD 322

  Fly   381 EILPICVP--KDPIPLHNHPLQIAGWGYT-KNREYSQVLLHNTVYE--NRYYCQDK--ISFFRNE 438
            .:..:|:|  :...|..:. ..::|||:| .:..||..:|.:||..  :...|...  .|.....
Human   323 TVGAVCLPAKEQHFPKGSR-CWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTP 386

  Fly   439 SQICASGIRGE-DSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDRKPGVYTKTGAFFSW 502
            ..:||..:.|. |:|:|||||||:....:.::    |.|:||:|........||||.|...|..|
Human   387 RMLCAGYLDGRADACQGDSGGPLVCPDGDTWR----LVGVVSWGRGCAEPNHPGVYAKVAEFLDW 447

  Fly   503 I 503
            |
Human   448 I 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	71/254 (28%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	11/63 (17%)
		Tryp_SPc	217..448	CDD:214473	70/256 (27%)