Protein Alignment CG10232 and KLK6

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 70/259 - (27%)
• Similarity: 117/259 - (45%)
• Gaps: 43/259 - (16%)

  Fly   256 RMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRV 320
            ::.:|.......:|:.|.|......|      |.|.||:..:|||||||    |..|.     :|
Human    21 KLVHGGPCDKTSHPYQAALYTSGHLL------CGGVLIHPLWVLTAAHC----KKPNL-----QV 70

  Fly   321 RLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRYTHEILPI 385
            .||:|::..........:.....         :|..| :.:..:.||.|:||..|.:.:..|.|:
Human    71 FLGKHNLRQRESSQEQSSVVRAV---------IHPDY-DAASHDQDIMLLRLARPAKLSELIQPL 125

  Fly   386 CVPKDPIPLHNHPLQIAGWGYTKNREYSQVL----LHNTVYENRYYCQDKISFFRNESQICASGI 446
            .:.:| ...:.....|.|||.|.:.::...:    :|   ..:|..|:........::.:||...
Human   126 PLERD-CSANTTSCHILGWGKTADGDFPDTIQCAYIH---LVSREECEHAYPGQITQNMLCAGDE 186

  Fly   447 R-GEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWIKANLK 508
            : |:|||:|||||||:.   .|     :|.|:||:|:..||.: ||||||....:.:||:..::
Human   187 KYGKDSCQGDSGGPLVC---GD-----HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	70/251 (28%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	68/250 (27%)