Protein Alignment CG10232 and PRSS2

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 75/273 - (27%)
• Similarity: 114/273 - (41%)
• Gaps: 73/273 - (26%)

  Fly   260 GTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLR------ 318
            |.....|..|:..       .|::..:.|.||||::::|::|.||.  ...:|:.|..|
Human    27 GYICEENSVPYQV-------SLNSGYHFCGGSLISEQWVVSAGHCY--KSAINSKLSGRGCEYHR 82

  Fly   319 -RVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNV-----HEQYFNTSRFESDIALVRLQTPVR 377
             :||||||:|..              :|...::.|.     |.:| |:...::||.|::|.:|..
Human    83 IQVRLGEHNIEV--------------LEGNEQFINAAKIIRHPKY-NSRTLDNDILLIKLSSPAV 132

  Fly   378 YTHEILPICVPKDPIPLHNHPLQIAGWGYTKNREYSQVLLHNTVYENRYYCQD------------ 430
            ....:..|.:|..| |.......|:|||.|        |.....|.:...|.|
Human   133 INSRVSAISLPTAP-PAAGTESLISGWGNT--------LSSGADYPDELQCLDAPVLSQAECEAS 188

  Fly   431 ---KISFFRNESQICASGIR-GEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDRKPG 491
               ||:    .:..|...:. |:|||:||||||::  .|.:.|      ||||:|.......:||
Human   189 YPGKIT----NNMFCVGFLEGGKDSCQGDSGGPVV--SNGELQ------GIVSWGYGCAQKNRPG 241

  Fly   492 VYTKTGAFFSWIK 504
            ||||...:..|||
Human   242 VYTKVYNYVDWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	75/273 (27%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	75/273 (27%)