Protein Alignment CG10232 and PROC

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 132/545 - (24%)
• Similarity: 206/545 - (37%)
• Gaps: 184/545 - (33%)

  Fly    31 KKCDVNEDCTHLKACPPLKYFLQSADIS---WAREAILRDKQC---------------------G 71
            ::| :.|.|...:|    |...|:.|.:   |::.  :...||                     |
Human   118 REC-IEEICDFEEA----KEIFQNVDDTLAFWSKH--VDGDQCLVLPLEHPCASLCCGHGTCIDG 175

  Fly    72 YNSYCCR-KEGYERRSNEQCVMLNDCPQFNGRKW----------------TSDILKSIINKICYI 119
            ..|:.|. :.|:|.|.         |.:..|.:|                ||.....
Human   176 IGSFSCDCRSGWEGRF---------CQRGEGERWMLAGGGAGLGPGWGRGTSTSCPR-------- 223

  Fly   120 DHFQPLVRRRVYVNCQRQEIFPCQY--DEICRSRDSC-PFLKLKRKKAQNILMSRQCGINTYCCP 181
               .||.....::||.........|  :|:...|.|| |..||    ..::|.         |.|
Human   224 ---PPLPAEVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKL----GDDLLQ---------CHP 272

  Fly   182 KQEFPDCPADEKCIRLDKCLRIH-NTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLP 245
            ..:|| |....|  |::| .|.| ....||       ::..:|.|.||
Human   273 AVKFP-CGRPWK--RMEK-KRSHLKRDTED-------QEDQVDPRLID----------------- 309

  Fly   246 TSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKM 310
                          |...|..:.||..:|:...::|:     |...||:..:|||||||:.:.|.
Human   310 --------------GKMTRRGDSPWQVVLLDSKKKLA-----CGAVLIHPSWVLTAAHCMDESKK 355

  Fly   311 VNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTP 375
            :       .|||||:|:......:         :::.|:...||..| :.|..::||||:.|..|
Human   356 L-------LVRLGEYDLRRWEKWE---------LDLDIKEVFVHPNY-SKSTTDNDIALLHLAQP 403

  Fly   376 VRYTHEILPICVPKDPIPLH--NHPLQ---IAGWGYTKNREYS--------------QVLLHNTV 421
            ...:..|:|||:|...:...  |...|   :.||||..:||..              .|:.||.
Human   404 ATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNE- 467

  Fly   422 YENRYYCQDKISFFRNESQICASGIRG--EDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSEN 484
                  |.:.:|...:|:.:|| ||.|  :|:||||||||::.:.:..:    :|.|:||:| |.
Human   468 ------CSEVMSNMVSENMLCA-GILGDRQDACEGDSGGPMVASFHGTW----FLVGLVSWG-EG 520

  Fly   485 CG-DRKPGVYTKTGAFFSWIKANLK 508
            || ....|||||...:..||..:::
Human   521 CGLLHNYGVYTKVSRYLDWIHGHIR 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	82/267 (31%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503	8/36 (22%)
		EGF_CA	162..193	CDD:238011	6/39 (15%)
		FXa_inhibition	235..270	CDD:464251	10/47 (21%)
		Tryp_SPc	308..543	CDD:238113	84/300 (28%)