Protein Alignment CG10232 and Hgfac

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_006504094.1
• Gene: Hgfac / 54426
• MGIID: 1859281
• Length: 658
• Species: Mus musculus
• Alignment Length: 563
• Identity: 133/563 - (23%)
• Similarity: 198/563 - (35%)
• Gaps: 194/563 - (34%)

  Fly    37 EDCTHLKACPPLKYFLQSADISWAREAILRDKQCGY----------------------------- 72
            :||...|.....:|........|||.:....:|||.
Mouse   192 KDCGTEKCFDETRYEYFEVGDHWARVSEGHVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLI 256

  Fly    73 ----NSYCCRKEGYERR-----SNEQCVMLNDCPQFNG-----------RKWTSDILKSIINKIC 117
                .|.|....||..|     ..|.| .|.:..::.|           ..|.||:|
Mouse   257 VGTGTSVCTCPLGYAGRFCNIVPTEHC-FLGNGTEYRGVASTAASGLSCLAWNSDLL-------- 312

  Fly   118 YIDHFQPLVRRRVYVNCQRQEIFPCQYDEICRSRDSCPFLKLKRKKAQNILMSRQCGINTYC--C 180
                                      |.|:  ..||.         |..:|:.  .|.:.||  .
Mouse   313 --------------------------YQEL--HVDSV---------AAAVLLG--LGPHAYCRNP 338

  Fly   181 PKQEFPDC-------PADEKCIRLDKC---LRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYI 235
            .|.|.|.|       .:.|.| ||..|   .|:|:.|.|..|.|
Mouse   339 DKDERPWCYVVKDNALSWEYC-RLTACESLARVHSQTPEILAAL--------------------- 381

  Fly   236 CCPEPGNVLPTSCGQ--------APPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSL 292
              ||....:..:||:        .|   |:..|:::.|..:||:|.:...|       :.|:|||
Mouse   382 --PESAPAVRPTCGKRHKKRTFLRP---RIIGGSSSLPGSHPWLAAIYIGN-------SFCAGSL 434

  Fly   293 INKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQY 357
            ::..:|::||||.......::..|:    ||:|......|...|         .|||.:..:..|
Mouse   435 VHTCWVVSAAHCFANSPPRDSITVV----LGQHFFNRTTDVTQT---------FGIEKYVPYTLY 486

  Fly   358 --FNTSRFESDIALVRL-----QTPVRYTHEILPICVPK--DPIPLHNHPLQIAGWGY------- 406
              ||.:  ..|:.|:||     :..|| :..:.|||:|:  ...|. .|..||||||:
Mouse   487 SVFNPN--NHDLVLIRLKKKGERCAVR-SQFVQPICLPEAGSSFPT-GHKCQIAGWGHMDEMQSS 547

  Fly   407 TKNREYSQVLLH---NTVYENRYYCQDKISFFRNESQICASGIR-GEDSCEGDSGGPLMLTLNND 467
            |....||..||.   ..|.:::....:......:.:.:||.... ..|:|:|||||||:...|.
Mouse   548 TDVSSYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLVCEKNG- 611

  Fly   468 YQDIVYLAGIVSYGSENCGD-RKPGVYTKTGAFFSWIKANLKP 509
               :.||.||:|:| :.||. .||||||:...:..||...::|
Mouse   612 ---VAYLYGIISWG-DGCGRLNKPGVYTRVANYVDWINDRIRP 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	79/266 (30%)
Hgfac	XP_006504094.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011	0/1 (0%)
		FN1	197..237	CDD:238018	8/39 (21%)
		EGF_CA	242..275	CDD:238011	5/32 (16%)
		Kringle	283..364	CDD:395005	24/129 (19%)
		Tryp_SPc	406..646	CDD:238113	79/268 (29%)