Protein Alignment CG10232 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 470
• Identity: 112/470 - (23%)
• Similarity: 184/470 - (39%)
• Gaps: 110/470 - (23%)

  Fly    59 WAREAILRDKQCGYNSYCCRKEGYERRSNEQCVMLNDCPQFNGRKWTSDILKSIINKICYIDHFQ 123
            |.......:.:||.:..|.       .|:..|..:..||  ||..          ...|...:.|
Mouse   108 WDSNCSTSEMECGSSGTCI-------SSSLWCDGVAHCP--NGED----------ENRCVRLYGQ 153

  Fly   124 PLVRRRVYVNCQRQEIFPCQYDEICRS--RDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFP 186
            ..: .:|| :.||:..:|...|:...|  |.:|..:..|.              |.|  ..|..|
Mouse   154 SFI-LQVY-SSQRKAWYPVCQDDWSESYGRAACKDMGYKN--------------NFY--SSQGIP 200

  Fly   187 DCPADEKCIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLPTSCG-- 249
            |.......::|:    :.:..::....|..:..|:  :|.:.|     :.|.|        ||
Mouse   201 DQSGATSFMKLN----VSSGNVDLYKKLYHSDSCS--SRMVVS-----LRCIE--------CGVR 246

  Fly   250 QAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTD 314
            ......|:..|..|.|.::||...|..:.      .:.|.||:|...:::||||||
Mouse   247 SVKRQSRIVGGLNASPGDWPWQVSLHVQG------VHVCGGSIITPEWIVTAAHCV--------- 296

  Fly   315 LVLRRVRLGEHDITTNPD--CDFTGNCAAPFVEIG----IEYFNVHEQYFNTSRFESDIALVRLQ 373
                      .:..::|.  ..|.|......:..|    :|....|..|.:.:: .:||||::||
Mouse   297 ----------EEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTK-NNDIALMKLQ 350

  Fly   374 TPVRYTHEILPICVPKDPIPLH-NHPLQIAGWGYTKNR-EYSQV-------LLHNTVYENRYYCQ 429
            ||:.:...:.|:|:|...:.|. :....|:|||.|..: :.|.|       |:..:...::|...
Mouse   351 TPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYN 415

  Fly   430 DKISFFRNESQICASGIRGE-DSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDRKPGVY 493
            :.|:    .:.|||..::|. |||:||||||| :||.|   .|.:|.|..|:||......:||||
Mouse   416 NLIT----PAMICAGFLQGSVDSCQGDSGGPL-VTLKN---GIWWLIGDTSWGSGCAKALRPGVY 472

  Fly   494 TKTGAFFSWIKANLK 508
            .....|..||...::
Mouse   473 GNVTVFTDWIYQQMR 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	75/261 (29%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060	9/53 (17%)
		SRCR_2	152..247	CDD:464747	25/131 (19%)
		Tryp_SPc	254..485	CDD:238113	75/264 (28%)