Protein Alignment CG10232 and KLK12

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 89/283 - (31%)
• Similarity: 119/283 - (42%)
• Gaps: 70/283 - (24%)

  Fly   243 VLPTSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVK 307
            ||..|....|.::.   ||....|..||...| :|...|     .|.|.||:.|:|||||||...
Human    11 VLGLSQAATPKIFN---GTECGRNSQPWQVGL-FEGTSL-----RCGGVLIDHRWVLTAAHCSGS 66

  Fly   308 DKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNV-HEQYFNTS-RFESDIALV 370
            ...         ||||||.::   ..|:|       .:|....|:| |..|...| ..|.|:.|:
Human    67 RYW---------VRLGEHSLS---QLDWT-------EQIRHSGFSVTHPGYLGASTSHEHDLRLL 112

  Fly   371 RLQTPVRYTHEILPICVPKDPIPLHNHPLQIAGWGYTKNREYS----------QVLLHNT---VY 422
            ||:.|||.|..:.|:.:|.| .........::|||.|.:....          .::.|.|   ||
Human   113 RLRLPVRVTSSVQPLPLPND-CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVY 176

  Fly   423 ENRYYCQDKISFFRNESQICASGIRGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSEN-CG 486
            ..|.          ..:.:||.|:.|:|:|:|||||||:..        ..|.|:||:||.. ||
Human   177 PGRI----------TSNMVCAGGVPGQDACQGDSGGPLVCG--------GVLQGLVSWGSVGPCG 223

  Fly   487 -DRKPGVY------TKTGAFFSW 502
             |..||||      |..|...||
Human   224 QDGIPGVYTYICNSTLVGLGTSW 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	85/266 (32%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	81/260 (31%)