DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10232 and CG9733

DIOPT Version :9

Sequence 1:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	142/498 - (28%)
Similarity:	206/498 - (41%)	Gaps:	143/498 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 CTHLKACPPLKYFLQSADISWAREAILRDKQCGYNSYCCRKEGYERRSNEQ---CVMLNDCPQFN 100
            |..:..|..|...|:.|.::...::.::...||            |.||.|   |     |.|..
  Fly    35 CVLINECQTLYSVLKRATLTDQEKSFIKSSACG------------RGSNNQPYVC-----CTQDT 82

  Fly   101 GRKWTSDILKSIINKICYIDHFQPLVRRRVYVNCQRQE-------IFPCQYDEICRSRDSCPFLK 158
            |                             ||..|||:       .|...::|
  Fly    83 G-----------------------------YVRIQRQDRTFPDYGAFGGDWEE------------ 106

  Fly   159 LKRKKAQNILMSRQCGINTYCCPKQE-----FPDCPADEKCIRLDKCLRIHNTTMEDGANLMDNR 218
               ::.|:.:.           |:||     |.:.||..:       .....::..||::|:
  Fly   107 ---ERPQSFVF-----------PRQERRPWSFGNQPATSR-------TPFRKSSTSDGSSLL--- 147

  Fly   219 QCAIDTRRIDSDKRHYICCPEPGNVLPTSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLST 283
                               |:     |.|||......|:..|.....||:|||.:|.|..|..:.
  Fly   148 -------------------PQ-----PPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNG 188

  Fly   284 MTNNCSGSLINKRYVLTAAHCVVK--DKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVE- 345
            ::..|:|||||:|||||||||:..  ::.|.|   |..|||||||..|..||...|...:|.|:
  Fly   189 LSTACAGSLINRRYVLTAAHCLTGRIEREVGT---LVSVRLGEHDTRTAVDCPPGGGSCSPEVQR 250

  Fly   346 IGIEYFNVHEQYF-NTSRFESDIALVRLQTPVRYTHEILPICVPKDPIPLHN----HPLQIAGWG 405
            :|.|...|||:|. ..|....||.|:|::..|||:..|.|||:|.. :.|.:    ....:||||
  Fly   251 LGFEEIRVHERYSEKASNQVHDIGLIRMERNVRYSDNIQPICLPSS-VGLESRQSGQQFTVAGWG 314

  Fly   406 YTKNREYSQVLLHNTV-YENRYYCQDKISFFR---NESQICASGIRGEDSCEGDSGGPLMLTLNN 466
            .|.....|.|....|| |.:...|:.:.|..:   ..:|:||.|...:|||:||||||||...:.
  Fly   315 RTLKMARSAVKQKVTVNYVDPAKCRQRFSQIKVNLEPTQLCAGGQFRKDSCDGDSGGPLMRFRDE 379

  Fly   467 DYQDIVYLAGIVSYGSENCGDRK-PGVYTKTGAFFSWIKANLK 508
            .:    .|.||||:|.: ||.:. |||||...|:..||:.|::
  Fly   380 SW----VLEGIVSFGYK-CGLKDWPGVYTNVAAYDIWIRQNVR 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	103/258 (40%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	101/255 (40%)
CG9733	NP_651784.2	CLIP	25..78	CDD:288855	12/59 (20%)
		Tryp_SPc	161..412	CDD:214473	102/259 (39%)
		Tryp_SPc	162..415	CDD:238113	103/261 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5140
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.920