Protein Alignment CG10232 and KLK2

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 81/286 - (28%)
• Similarity: 119/286 - (41%)
• Gaps: 66/286 - (23%)

  Fly   244 LPTSCGQAPPLY--RMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVV 306
            |...|..|.||.  |:..|.....:..||. :.:|     |....:|.|.|::.::|||||||:.
Human    10 LSVGCTGAVPLIQSRIVGGWECEKHSQPWQ-VAVY-----SHGWAHCGGVLVHPQWVLTAAHCLK 68

  Fly   307 KDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFE------- 364
            |:.         :|.||.|::....|   ||.      .:.:.:...|..| |.|..:
Human    69 KNS---------QVWLGRHNLFEPED---TGQ------RVPVSHSFPHPLY-NMSLLKHQSLRPD 114

  Fly   365 ----SDIALVRLQTPVRYTHEILPICVPKDPIPLHNHPLQIAGWGYTKNREY---------SQVL 416
                .|:.|:||..|.:.|..:..:.:|... |........:|||..:..|:         |..|
Human   115 EDSSHDLMLLRLSEPAKITDVVKVLGLPTQE-PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHL 178

  Fly   417 LHNTVYENRYYCQDKISFFRNESQICASGI--RGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVS 479
            |.|.:....|  .:|::    |..:|| |:  .|:|:|.|||||||:..        ..|.||.|
Human   179 LSNDMCARAY--SEKVT----EFMLCA-GLWTGGKDTCGGDSGGPLVCN--------GVLQGITS 228

  Fly   480 YGSENCG-DRKPGVYTKTGAFFSWIK 504
            :|.|.|. ..||.||||...:..|||
Human   229 WGPEPCALPEKPAVYTKVVHYRKWIK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	75/268 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	75/271 (28%)