Protein Alignment CG10232 and KLK1

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 75/290 - (25%)
• Similarity: 117/290 - (40%)
• Gaps: 84/290 - (28%)

  Fly   249 GQAPPLY-RMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVN 312
            |.|||:. |:..|.....:..||.|.|.:.:      |..|.|.|:::::|||||||:..:
Human    16 GAAPPIQSRIVGGWECEQHSQPWQAALYHFS------TFQCGGILVHRQWVLTAAHCISDN---- 70

  Fly   313 TDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQY----FNTSRFES-------- 365
                 .::.||.|::       |.....|.||       :|.|.:    ||.|..|:
Human    71 -----YQLWLGRHNL-------FDDENTAQFV-------HVSESFPHPGFNMSLLENHTRQADED 116

  Fly   366 ---DIALVRLQTPV-RYTHEILPICVPKDPIPLHNHPLQIAGWGYTKNREYSQVLLHNTVYENRY 426
               |:.|:||..|. ..|..:..:.:|.:. |........:|||..:...:|        :.:..
Human   117 YSHDLMLLRLTEPADTITDAVKVVELPTEE-PEVGSTCLASGWGSIEPENFS--------FPDDL 172

  Fly   427 YCQD---------------KISFFRNESQICASGIR-GEDSCEGDSGGPLMLTLNNDYQDIVYLA 475
            .|.|               |::.|    .:|...:. |:|:|.||||||||.       |.| |.
Human   173 QCVDLKILPNDECKKAHVQKVTDF----MLCVGHLEGGKDTCVGDSGGPLMC-------DGV-LQ 225

  Fly   476 GIVSYGSENCG-DRKPGVYTKTGAFFSWIK 504
            |:.|:|...|| ..||.|..:..::..||:
Human   226 GVTSWGYVPCGTPNKPSVAVRVLSYVKWIE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	70/278 (25%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	70/281 (25%)