Protein Alignment CG10232 and TMPRSS7

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001382436.1
• Gene: TMPRSS7 / 344805
• HGNCID: 30846
• Length: 843
• Species: Homo sapiens
• Alignment Length: 631
• Identity: 135/631 - (21%)
• Similarity: 224/631 - (35%)
• Gaps: 212/631 - (33%)

  Fly    10 IQGFLLSLSFGRVQLQ----------VYNS---------WKKCD----------------VNEDC 39
            |.|:|:.||...:|::          :|:|         ::.|:                |....
Human   280 IVGYLIRLSIKSIQIEADNCVTDSLTIYDSLLPIRSSILYRICEPTRTLMSFVSTNNLMLVTFKS 344

  Fly    40 THLKACPPLKYFLQSADISWAREAILRDKQCGYNSYCCRKEGYERRSNEQCVMLNDCPQFNGR-- 102
            .|::....::.:.:          ::.:::|                 |..|::.|...|.|:
Human   345 PHIRRLSGIRAYFE----------VIPEQKC-----------------ENTVLVKDITGFEGKIS 382

  Fly   103 --------------KW-------TSDILKSIIN--------KIC---------------YIDHFQ 123
                          .|       |..|.....|        |.|               |:||
Human   383 SPYYPSYYPPKCKCTWKFQTSLSTLGIALKFYNYSITKKSMKGCEHGWWEINEHMYCGSYMDH-- 445

  Fly   124 PLVRRRVYVNCQRQEIF----PCQYDEI-CRSRDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQ 183
                         |.||    |..:.:: |.||.|...| |....:.||  |:.|.:.::.|...
Human   446 -------------QTIFRVPSPLVHIQLQCSSRLSDKPL-LAEYGSYNI--SQPCPVGSFRCSSG 494

  Fly   184 EFPDC-PADEKCIRLDKC--------------------LRIHNTTMEDG----ANLMDNRQCAID 223
            .   | |..::|..::.|                    .|.|...:.||    .|..|.:.|
Human   495 L---CVPQAQRCDGVNDCFDESDELFCVSPQPACNTSSFRQHGPLICDGFRDCENGRDEQNC--- 553

  Fly   224 TRRIDSDKRHYIC------------------CPEPGNVLPTSCGQ-APPLYRMAYGTAARPNEYP 269
            |:.|..:.|.:.|                  ||:..:....:|.: :..|:|:..||......:|
Human   554 TQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCSRSSSALHRIIGGTDTLEGGWP 618

  Fly   270 WMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNPDCD 334
            |...|.:..      :..|..|:|::.::|:||||...:::  :|.......||.:
Human   619 WQVSLHFVG------SAYCGASVISREWLLSAAHCFHGNRL--SDPTPWTAHLGMY--------- 666

  Fly   335 FTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQT--PVRYTHEILPICVPKDPIPLHN- 396
            ..||  |.||. .:....||| |:|:..|:.||||::|..  |......|.|||:|.....:.:
Human   667 VQGN--AKFVS-PVRRIVVHE-YYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSG 727

  Fly   397 HPLQIAGWG--YTKNREYSQVLLHNTV-YENRYYCQDKISFFRNESQICASGIRGE-DSCEGDSG 457
            ....:.|||  :..:.:.|.||....| ..::..|........:. .:||..:.|: |:|:||||
Human   728 EKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIITSR-MLCAGIMSGKRDACKGDSG 791

  Fly   458 GPLMLTLNNDYQDIVYLAGIVSYGSENCGDRKPGVYTKTGAFFSWI 503
            |||.....:|.:.|  |.||||:|..:.....|||||:...|..||
Human   792 GPLSCRRKSDGKWI--LTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	74/251 (29%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..67
		SEA	108..207	CDD:460188
		CUB	247..359	CDD:238001	11/88 (13%)
		LDLa	484..518	CDD:238060	6/36 (17%)
		LDLa	559..594	CDD:238060	4/34 (12%)
		Tryp_SPc	605..835	CDD:214473	73/253 (29%)