Protein Alignment CG10232 and HPN

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 97/334 - (29%)
• Similarity: 142/334 - (42%)
• Gaps: 74/334 - (22%)

  Fly   211 GANLMDNRQCAIDTRRIDSDKRHY----IC-CPEPGNVLPT---SCGQAP-PLYRMAYGTAARPN 266
            |||......| :|..|:...:|..    :| ||. |..|..   .||:.. |:.|:..|......
Human   110 GANGTSGFFC-VDEGRLPHTQRLLEVISVCDCPR-GRFLAAICQDCGRRKLPVDRIVGGRDTSLG 172

  Fly   267 EYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNP 331
            .:||...|.|:...|      |.|||::..:|||||||     ....:.||.|.|:
Human   173 RWPWQVSLRYDGAHL------CGGSLLSGDWVLTAAHC-----FPERNRVLSRWRV--------- 217

  Fly   332 DCDFTGNC--AAPF-VEIGIEYFNVHEQYF-----NTSRFESDIALVRLQTPVRYTHEILPICVP 388
               |.|..  |:|. :::|::....|..|.     |:....:|||||.|.:|:..|..|.|:|:|
Human   218 ---FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 279

  Fly   389 KDPIPLHNHPL-QIAGWGYTKN--------REYSQVLLHNTVYENRYYCQDKISFFRNE---SQI 441
            .....|.:..: .:.|||.|:.        :|....::.|.|      | :...|:.|:   ...
Human   280 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDV------C-NGADFYGNQIKPKMF 337

  Fly   442 CASGIRGE-DSCEGDSGGPLMLTLNNDYQDIV------YLAGIVSYGSENCGDRKPGVYTKTGAF 499
            ||....|. |:|:||||||.:.      :|.:      .|.||||:|:.....:|||||||...|
Human   338 CAGYPEGGIDACQGDSGGPFVC------EDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDF 396

  Fly   500 FSWIKANLK 508
            ..||...:|
Human   397 REWIFQAIK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	80/272 (29%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	14/50 (28%)
		Tryp_SPc	163..400	CDD:238113	78/272 (29%)