Protein Alignment CG10232 and F12

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001014028.1
• Gene: F12 / 306761
• RGDID: 1359175
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 135/564 - (23%)
• Similarity: 206/564 - (36%)
• Gaps: 182/564 - (32%)

  Fly    31 KKCDVNEDCTHLKACPPLKYFLQSADISWAREA-----------------ILRDKQCGYNSYCCR 78
            |.|. .|.|...:.   ||:|.::.  .|.|..                 :|..:.|..|.  |.
  Rat   127 KHCQ-REKCFESQL---LKFFHENE--IWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNP--CL 183

  Fly    79 KEGYERRSNEQCVMLND-----CPQFNGRKWTSDILKSIINKICYIDHFQPLVRRRVYVNCQRQE 138
            ..|       .|:::.|     ||......:....||:    .||.|       |.:....|.:.
  Rat   184 NGG-------TCLLVEDHRLCHCPAGYAGPFCDLDLKA----TCYED-------RGLSYRGQAKT 230

  Fly   139 IF---PCQYDEICRSRDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFPDCPADEKC------ 194
            ..   |||     |......:..:...:|    :|...|.:.:|    ..||......|
  Rat   231 TLSGAPCQ-----RWASEATYRNMTETQA----LSWGLGHHAFC----RNPDNDTRPWCYVWSGD 282

  Fly   195 -IRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRID-SDKRHYICCPEP----------------- 240
             :..|.|               |..||.:.|.... |.:.|.:..|.|
  Rat   283 RLSWDYC---------------DLEQCQMPTLTSPVSPESHDMLKPRPPILQMPQFPSLSDALDN 332

  Fly   241 ----GNVLPTS----CGQ-----APPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSL 292
                .||:..:    |||     ...|.|:..|..|.|..:|::|.|.:.:       :.|:|||
  Rat   333 STRNQNVVSRTSTVVCGQRFRKRLSSLRRVVGGLVALPGSHPYIAALYWGD-------SFCAGSL 390

  Fly   293 INKRYVLTAAHCVVKDKMVNTDLVLRRVRLGE--HDITTNPDCDFTGNCAAPFVEIGIEYFNVHE 355
            |:..:|||||||:.| :....:|.   |.||:  |    |..|:   .|..    :.:..:.:||
  Rat   391 IDPCWVLTAAHCLQK-RPAPEELT---VVLGQDRH----NQSCE---RCQT----LAVHSYRLHE 440

  Fly   356 QYFNTSRFESDIALVRLQ---------TPVRYTHEILPICVPKDPIPLHNHPL-QIAGWG--YTK 408
            . |::..::.|:||:||:         :|     .:.|:|:|....|.....| ::||||  :..
  Rat   441 G-FSSKTYQHDLALLRLRGRKNSCAILSP-----HVQPVCLPSSAAPPSETVLCEVAGWGHQFEG 499

  Fly   409 NREYSQVLLHNTVYENRYYCQDKISFFRNES-----------QICASGIR-GEDSCEGDSGGPLM 461
            ..||:..|....|        ..||..|..|           .:||..:. |.|:|:|||||||:
  Rat   500 AEEYATFLQEAQV--------PFISLDRCSSSNVHGDAILPGMLCAGFLEGGADACQGDSGGPLV 556

  Fly   462 LTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWIK 504
            .......:.:. |.|::|:|| .|||| ||||||....:..||:
  Rat   557 CDEGVTERQLT-LRGVISWGS-GCGDRNKPGVYTDVANYLDWIQ 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	82/272 (30%)
F12	NP_001014028.1	FN2	40..87	CDD:238019
		EGF_CA	95..130	CDD:238011	1/2 (50%)
		FN1	132..170	CDD:238018	7/42 (17%)
		EGF	177..207	CDD:394967	8/38 (21%)
		Kringle	216..294	CDD:395005	19/112 (17%)
		Tryp_SPc	362..600	CDD:238113	82/275 (30%)