DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10232 and F10

DIOPT Version :9

Sequence 1:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	477	Identity:	112/477 - (23%)
Similarity:	184/477 - (38%)	Gaps:	148/477 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 QC--GYNSYCCR-KEGYERRSNEQCVMLNDCPQFNGRKWTSDILKSIINKICYIDHFQPLVRRRV 130
            :|  |..||.|. .||:|.:         :|..|             :.|:|.:|:
  Rat   100 ECRDGLGSYTCTCTEGFEGK---------NCELF-------------VRKLCSLDN--------- 133

  Fly   131 YVNCQRQEIFPCQYDEICRSRD-----SCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFPDCPA 190
             .:|          |:.||...     ||         |:...:...   ...|.....||
  Rat   134 -GDC----------DQFCREEQNSVVCSC---------AKGYFLGND---GKSCLSTAPFP---- 171

  Fly   191 DEKCIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLPTSC------- 248
               |.:.:|.              ...|..|::|...:.|....:  |:...:.||..
  Rat   172 ---CGKTNKG--------------RAKRSVALNTSNSEPDPEDLM--PDADILYPTESPSELLNL 217

  Fly   249 ------GQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNN-CSGSLINKRYVLTAAHCVV 306
                  ..:..:.|:..|...:..|.||.|:|..:..     |:. |.|:::|:.|:||||||:.
  Rat   218 NKTEPEANSDDVIRIVGGQECKRGECPWQALLFSDEE-----TDGFCGGTILNEFYILTAAHCLH 277

  Fly   307 KDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHE-------QYFNTSRFE 364
            :.|..       :||:|  |:.|..             |.|.|.  |||       ..|....::
  Rat   278 QAKRF-------KVRVG--DLNTEQ-------------EDGGEM--VHEVDMIIKHNKFQRDTYD 318

  Fly   365 SDIALVRLQTPVRYTHEILPICVPK----DPIPLHNHPLQIAGWGYT--KNREYSQVLLHNTVYE 423
            .|||::||:||:.:...:.|.|:|:    :...:......::|:|.|  |.|:...:.:....|.
  Rat   319 FDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYV 383

  Fly   424 NRYYCQDKISFFRNESQICAS-GIRGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGD 487
            :|..|:...||...::..||. ..:.||:|:||||||.:    ..::|..::.||||:| |.|..
  Rat   384 DRNTCRLSTSFSITQNMFCAGYDAKQEDACQGDSGGPHV----TRFKDTYFVTGIVSWG-EGCAR 443

  Fly   488 R-KPGVYTKTGAFFSWIKANLK 508
            : |.|:|||..||..||..::|
  Rat   444 KGKYGIYTKVTAFLKWIDRSMK 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	78/261 (30%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	76/258 (29%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011	8/30 (27%)
		FXa_inhibition	129..164	CDD:405372	9/66 (14%)
		Tryp_SPc	232..462	CDD:238113	78/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920