Protein Alignment CG10232 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 90/293 - (30%)
• Similarity: 129/293 - (44%)
• Gaps: 66/293 - (22%)

  Fly   241 GNVLPTSCGQAP-----PLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLT 300
            |......||.||     ...|:..||.|:...:||:..|..:..|:  :.:.|.|:|:.:|:|||
Human    57 GGAHAEDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRV--LVHVCGGTLVRERWVLT 119

  Fly   301 AAHCVVKDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSR--- 362
            |||| .||.   :|.::....:|     ||                     |:|.:|.:|.:
Human   120 AAHC-TKDA---SDPLMWTAVIG-----TN---------------------NIHGRYPHTKKIKI 154

  Fly   363 -------------FESDIALVRLQTPVRYTHEILPICVPKDPIPL--HNHPLQIAGWGYTKNREY 412
                         :.:||||..|:..|||...|.|||:|.|...:  .|....|:|||.||....
Human   155 KAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGN 219

  Fly   413 SQVLLHNTV--YENRYYCQDKISF---FRNESQICASGIRGE-DSCEGDSGGPLMLTLNNDYQDI 471
            :..:|.:..  |.:|..|..:.|:   ..|.| .||....|. |:|.||||||||..| .:|:..
Human   220 ATNILQDAEVHYISREMCNSERSYGGIIPNTS-FCAGDEDGAFDTCRGDSGGPLMCYL-PEYKRF 282

  Fly   472 VYLAGIVSYGSENCGDRK-PGVYTKTGAFFSWI 503
             ::.||.||| ..||.|. ||||.....:..|:
Human   283 -FVMGITSYG-HGCGRRGFPGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	84/269 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	84/272 (31%)