DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10232 and f10

DIOPT Version :9

Sequence 1:NP_651175.4 Gene:CG10232 / 42800 FlyBaseID:FBgn0039108 Length:509 Species:Drosophila melanogaster
Sequence 2:NP_958870.3 Gene:f10 / 282670 ZFINID:ZDB-GENE-021206-9 Length:504 Species:Danio rerio


Alignment Length:526 Identity:125/526 - (23%)
Similarity:217/526 - (41%) Gaps:129/526 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 NSWKKCDVNEDCTHLKACPPLKYF--LQSADISWAR----EAIL-----RDKQC-----GYNSYC 76
            |..::| :.|.|.:.:|   .:.|  ::..|..|.:    :|.|     ...||     .|..:|
Zfish    49 NMEREC-IEERCNYEEA---REIFEDVKKTDEFWHKYVDGDACLSHPCVNGGQCKDAIGPYTCFC 109

  Fly    77 CRKEGYERRSNEQCVMLNDCPQFNGRKWTSDILKSIINKICYIDHFQPLVRRRVYVNCQR-QEIF 140
              ::|: :..|.:.|:...|...||.              |  |||..::.:.|..:|.. .|:.
Zfish   110 --QQGF-KGYNCEIVIPELCENENGG--------------C--DHFCEVMEKNVVCSCANGYELA 155

  Fly   141 PCQYDEICRSRDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQ------EFPDCPADEKCIRLDK 199
            |  ..:.|:|:|  ||               :||:   ..||:      ..|:....|       
Zfish   156 P--NGKSCQSQD--PF---------------KCGV---IYPKKTRSIFFHTPNITESE------- 191

  Fly   200 CLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLP--TSCGQAPPLYRMAYGTA 262
              ....|.:|.....:.|....::.:.......|.:...|...:||  ::.|..    |:..|..
Zfish   192 --NEEETELEATIEPVYNHSNPLNNQTDSMFGLHELEIIEEEPILPVVSTAGDG----RIVNGVE 250

  Fly   263 ARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDI 327
            ..|.:.||.|:||.||.     ...|.|:::.:.::|:||||      :|..|.: ||.:||:|.
Zfish   251 CPPGDCPWQALLINENN-----MGFCGGTILTEHFILSAAHC------MNESLSI-RVVVGEYDT 303

  Fly   328 TTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRYTHEILPICVPK--- 389
            ......:.|.:         ::...:|:.| ....:.:||||::|..|:::|..|:|.|:|:   
Zfish   304 LVPEGREATHD---------VDEILIHKNY-QPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKF 358

  Fly   390 -DPIPLHNHPLQIAGWGYTKNREYSQVLLHN-TV-YENRYYCQDKISFFRNESQICASGIRGE-D 450
             :.:.:......::|:|..:....|..:|.. || |.||..|.:..:|..:....||...:.| |
Zfish   359 AERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKD 423

  Fly   451 SCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWIK---------- 504
            :|:||||||.:....|.:    ::.|:||:| |.|..: |.||||:...:..||.          
Zfish   424 ACQGDSGGPHVTRFKNTW----FITGVVSWG-EGCARKGKYGVYTQVSKYIMWINNAMTKVMPET 483

  Fly   505 -ANLKP 509
             |:|||
Zfish   484 GASLKP 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10232NP_651175.4 Tryp_SPc 260..506 CDD:238113 73/264 (28%)
Tryp_SPc 260..503 CDD:214473 71/250 (28%)
f10NP_958870.3 GLA 19..82 CDD:214503 8/36 (22%)
EGF_CA 83..119 CDD:238011 8/38 (21%)
FXa_inhibition 126..161 CDD:291342 11/52 (21%)
Tryp_SPc 244..472 CDD:214473 72/254 (28%)
Tryp_SPc 245..474 CDD:238113 73/255 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D402896at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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