DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10232 and CG30091

DIOPT Version :9

Sequence 1:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	84/294 - (28%)
Similarity:	124/294 - (42%)	Gaps:	54/294 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 RRIDSDKRHYICCPEPGNVLPTSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNN-- 287
            |.:|.|      |..|..::|...|          |..|...:.||||::         .||:
  Fly    21 RLLDED------CGVPMQLIPKIVG----------GVDAGELKNPWMALI---------KTNDEF 60

  Fly   288 -CSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYF 351
             |.||:|..::|||||||:..|:..........|.||.:.:..      ||....|.....:|..
  Fly    61 ICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLA------TGEHNHPHEIYNVERV 119

  Fly   352 NVHEQYFNTSRFESDIALVRLQTPVRYTHEILPICVPKDPIPLHNHPLQ----------IAGWGY 406
            .:|:. |....:.:||||:|||..:.|..:|.|:|:      |.|..|:          ..|||.
  Fly   120 YIHDS-FAIQNYRNDIALLRLQKSIVYKPQIKPLCI------LLNDQLKPQTDLIQEFTAIGWGV 177

  Fly   407 TKNREYSQVLLHNTVYE-NRYYCQDKISFFRNESQICASGIRGEDSCEGDSGGPLMLTLNNDYQD 470
            |.|.:.|..|....:|. :|..|:....:..:....||....|.|:|:.||||||.:.:..|...
  Fly   178 TGNGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIK 242

  Fly   471 IVYLAGIVSYGSENCGDRKPGVYTKTGAFFSWIK 504
            .....||||.|:|:|  |..|:||.......:|:
  Fly   243 RATQLGIVSTGTEDC--RGFGMYTDVMGHIDFIE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	77/259 (30%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	76/256 (30%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	77/270 (29%)
		Tryp_SPc	37..276	CDD:238113	78/272 (29%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463565
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940