Protein Alignment CG10232 and F10

DIOPT Version :9

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 125/525 - (23%)
• Similarity: 207/525 - (39%)
• Gaps: 124/525 - (23%)

  Fly    47 PLKYFLQSADIS----WAREAILRDKQCGYNSYCCR-----------KEGYERRSNEQCVMLNDC 96
            ||...|.||.::    ......:|.:|.  |:...|           |:|:..|   :| |...|
Human     4 PLHLVLLSASLAGLLLLGESLFIRREQA--NNILARVTRANSFLEEMKKGHLER---EC-MEETC 62

  Fly    97 PQFNGRK--WTSDILKSIINKICYIDHFQPLVRRRVYVNCQRQEIFPCQYDEICR---SRDSCPF 156
            .....|:  ..||......||               |.:..:.|..|||....|:   ...:|..
Human    63 SYEEAREVFEDSDKTNEFWNK---------------YKDGDQCETSPCQNQGKCKDGLGEYTCTC 112

  Fly   157 LKLKRKKAQNILMSRQCGINTYCCPKQEFPDCPADEKCIRLDKCLRIHNTTMEDGANLMDNRQCA 221
            |:....|...:...:.|.::...|  .:|  |..::..: :..|.|        |..|.||.:..
Human   113 LEGFEGKNCELFTRKLCSLDNGDC--DQF--CHEEQNSV-VCSCAR--------GYTLADNGKAC 164

  Fly   222 IDT-------RRIDSDKRHYICCPEPGNVLPTSC----------------------GQAPP---- 253
            |.|       :.::..||............|.|.                      .|..|
Human   165 IPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGD 229

  Fly   254 --LYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLV 316
              |.|:..|...:..|.||.|:||.|...     ..|.|:::::.|:||||||:.:.|..
Human   230 NNLTRIVGGQECKDGECPWQALLINEENE-----GFCGGTILSEFYILTAAHCLYQAKRF----- 284

  Fly   317 LRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRYTHE 381
              :||:|:.:....     .|..|...||:.|::     ..|....::.|||::||:||:.:...
Human   285 --KVRVGDRNTEQE-----EGGEAVHEVEVVIKH-----NRFTKETYDFDIAVLRLKTPITFRMN 337

  Fly   382 ILPICVPK----DPIPLHNHPLQIAGWGYT--KNREYSQVLLHNTVYENRYYCQDKISFFRNESQ 440
            :.|.|:|:    :...:......::|:|.|  |.|:.:::.:....|.:|..|:...||...::.
Human   338 VAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 402

  Fly   441 ICAS-GIRGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWI 503
            .||. ..:.||:|:||||||.:    ..::|..::.||||:| |.|..: |.|:|||..||..||
Human   403 FCAGYDTKQEDACQGDSGGPHV----TRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWI 462

  Fly   504 KANLK 508
            ..::|
Human   463 DRSMK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	75/253 (30%)
		Tryp_SPc	260..503	CDD:214473	73/250 (29%)
F10	NP_000495.1	GLA	25..85	CDD:214503	15/80 (19%)
		EGF_CA	86..122	CDD:238011	8/35 (23%)
		FXa_inhibition	129..164	CDD:317114	10/47 (21%)
		O-glycosylated at one site	183..203		2/19 (11%)
		Tryp_SPc	235..464	CDD:238113	75/255 (29%)
		O-glycosylated at one site	476..485

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920