Protein Alignment CG10232 and F7

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 107/441 - (24%)
• Similarity: 169/441 - (38%)
• Gaps: 108/441 - (24%)

  Fly   128 RRVYVNCQRQEIFPCQYDE-------ICRSRDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEF 185
            |.::.:.:|.::|...|.:       .|::..||          ::.|.|..|    :|.|..|.
Human    81 REIFKDAERTKLFWISYSDGDQCASSPCQNGGSC----------KDQLQSYIC----FCLPAFEG 131

  Fly   186 PDCPADEKCIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPG--------- 241
            .:|...|......: |:...:....|:.:..:...|:.....|.|.: .||..|.|
Human   132 RNCETQESPASWRR-LKREASCWSSGSRMPGDLCSALVPSSPDKDDQ-LICVNENGGCEQYCSDH 194

  Fly   242 --------------------NVLPT---SCGQAP---------PLYRMAYGTAARPNEYPWMAML 274
                                :..||   .||:.|         |..|:..|......|.||..:|
Human   195 TGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLL 259

  Fly   275 IYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVN-TDLVLRRVRLGEHDITTNPDCDFTGN 338
            :....:|      |.|:|||..:|::||||.  ||:.| .:|:   ..|||||::.: |.|....
Human   260 LVNGAQL------CGGTLINTIWVVSAAHCF--DKIKNWRNLI---AVLGEHDLSEH-DGDEQSR 312

  Fly   339 CAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRYTHEILPICVPKDPIPLHNHPL---- 399
            ..|..:        :...|. ......||||:||..||..|..::|:|:|:..........
Human   313 RVAQVI--------IPSTYV-PGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFS 368

  Fly   400 QIAGWGYTKNREYS--QVLLHNTVYENRYYCQDKISFFR--------NESQICASGIRG-EDSCE 453
            .::|||...:|..:  ::::.|.   .|...||.:...|        .|...||....| :|||:
Human   369 LVSGWGQLLDRGATALELMVLNV---PRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCK 430

  Fly   454 GDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDRKPGVYTKTGAFFSWIK 504
            ||||||..    ..|:...||.||||:|.........||||:...:..|::
Human   431 GDSGGPHA----THYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQ 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	76/261 (29%)
F7	XP_011535776.2	GLA	36..97	CDD:214503	3/15 (20%)
		EGF_CA	99..135	CDD:238011	9/49 (18%)
		FXa_inhibition	180..216	CDD:464251	3/35 (9%)
		Tryp_SPc	242..478	CDD:238113	76/264 (29%)