Protein Alignment CG10232 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 95/359 - (26%)
• Similarity: 161/359 - (44%)
• Gaps: 73/359 - (20%)

  Fly   168 LMSRQCGINTYCCPKQEFPDCPADEKCIRLDKCLRIHNTTMEDGAN---------LMDNRQCAID 223
            |:....|.|.....|.:||  ||:...:|.....::|.....:.|:         ||:..:.|
Human   102 LLPNANGSNVQLQLKFKFP--PAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAA-- 162

  Fly   224 TRRIDSDKRHYICC-PEPGNVLPTSCGQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNN 287
                 |:.....|| .:..|.:.|.       .::..|.::....:||.|.:.::.|      :.
Human   163 -----SEMLTNNCCGRQVANSIITG-------NKIVNGKSSLEGAWPWQASMQWKGR------HY 209

  Fly   288 CSGSLINKRYVLTAAHCVV-----KDKMVNTDLVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIG 347
            |..|||:.|::|:||||..     ||..||..:|:.:                      |::...
Human   210 CGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNK----------------------PYMTRK 252

  Fly   348 IEYFNVHEQYFNTSRFESDIALVRLQTPVRYTHEILPICVPKDPIPL-HNHPLQIAGWG-YTKNR 410
            ::....||.| ::.....|||||:|...|.:|..|..||:|:..:.| .|..:.:.||| ...|.
Human   253 VQNIIFHENY-SSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNG 316

  Fly   411 EYSQVLLHN--TVYENRYYCQDKISF--FRNESQICASGIRGE-DSCEGDSGGPLMLTLNNDYQD 470
            .:..:|..:  .:.:|: .|....::  |..::.:||..:.|| |:|:.||||||...   |.::
Human   317 SFPVILQEDFLKIIDNK-ICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYP---DSRN 377

  Fly   471 IVYLAGIVSYGSENCGDR-KPGVYTKTGAFFSWI 503
            |.:|.||||:| :.||.: ||||||:..::.:||
Human   378 IWHLVGIVSWG-DGCGKKNKPGVYTRVTSYRNWI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	76/257 (30%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188	10/41 (24%)
		Tryp_SPc	185..413	CDD:238113	76/260 (29%)