Protein Alignment CG10232 and KLK8

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 93/328 - (28%)
• Similarity: 134/328 - (40%)
• Gaps: 71/328 - (21%)

  Fly   194 CIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPE--PGNVLPTSCGQAPPLY- 255
            |..||...:::          .:|..|.....:..|...|   ||.  ..|.||.:.|.:....
Human    25 CGSLDLLTKLY----------AENLPCVHLNPQWPSQPSH---CPRGWRSNPLPPAAGHSRAQED 76

  Fly   256 RMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRV 320
            ::..|...:|:..||.|.|....:.|      |.|.|:...:||||||| .|.|..        |
Human    77 KVLGGHECQPHSQPWQAALFQGQQLL------CGGVLVGGNWVLTAAHC-KKPKYT--------V 126

  Fly   321 RLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNTSRFES---DIALVRLQTPVRYTHEI 382
            |||:|.: .|.|        .|..||.:.....|..| |:|..|.   |:.|::|:.......::
Human   127 RLGDHSL-QNKD--------GPEQEIPVVQSIPHPCY-NSSDVEDHNHDLMLLQLRDQASLGSKV 181

  Fly   383 LPICVPKDPIPLHNHPLQ------IAGWG-YTKNREYSQVLLHNT---VYENRYYCQDKISFFRN 437
                   .||.|.:|..|      ::||| .|..||.....|:..   ::..: .|:|.......
Human   182 -------KPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQK-KCEDAYPGQIT 238

  Fly   438 ESQICASGIRGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCG-DRKPGVYTKTGAFFS 501
            :..:||...:|.|:|:|||||||:..        ..|.||.|:||:.|| ..||||||....:..
Human   239 DGMVCAGSSKGADTCQGDSGGPLVCD--------GALQGITSWGSDPCGRSDKPGVYTNICRYLD 295

  Fly   502 WIK 504
            |||
Human   296 WIK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	80/259 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	77/260 (30%)