Protein Alignment CG10232 and tmprss2.12

DIOPT Version :10

• Sequence 1: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_031752400.1
• Gene: tmprss2.12 / 100497514
• XenbaseID: XB-GENE-22065925
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 539
• Identity: 121/539 - (22%)
• Similarity: 189/539 - (35%)
• Gaps: 182/539 - (33%)

  Fly     2 VEVSVCFLIQGFL----LSLSFGRVQLQVYNSWKKCDVNEDCTHLKACPPLKYFLQSADISWARE 62
            :..::|.||...:    ||..||..        .||..:
 Frog    96 ISAALCVLIAAIIIIAVLSWHFGTA--------TKCQAS-------------------------- 126

  Fly    63 AILRDKQCGYNSYCCRKEGYERRSNEQCVMLNDCPQFNGRKWTSDILKSIINKIC---YIDHFQP 124
                   ||.:|.|.       ..::.|..:..||  ||...:|          |   |..:||
 Frog   127 -------CGSSSNCV-------LVSQWCDGVKHCP--NGEDESS----------CLRMYGPNFQ- 164

  Fly   125 LVRRRVYVNCQRQEIFPCQYDEICRSR--DSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFPD 187
                     .|........:..:|...  ||     :.|...|:|      |.::....|.....
 Frog   165 ---------LQAYSASKATWLPVCADNWGDS-----IGRTACQDI------GYSSSSYIKSNAVT 209

  Fly   188 CPADEKCIRLDKCLRIHNTTMEDGANLMDNRQCA----IDTRRIDSDKRHYICCPEPGNVLPTSC 248
            .||.:..:||:......|..    |:|..:..|:    :..:.||.....|
 Frog   210 APASDGYVRLNNYAGTGNIF----ASLNYSSTCSSGLVVSLKCIDCGLSTY-------------- 256

  Fly   249 GQAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNT 313
            |::    |:..|::|...::||...|.|::      ||.|.||:|...:::||||||..|
 Frog   257 GES----RIVGGSSASIGDWPWQVNLQYDD------TNLCGGSVIAANWIVTAAHCVQGD----- 306

  Fly   314 DLVLRRVRLGEHDITTNPDC--DFTGNCAAPFVEIGIEYFN----------VHEQYFNTSRFESD 366
                          |::|..  .|.|....|      .|::          ||..|.:.:. .:|
 Frog   307 --------------TSSPSLWKAFIGKIKMP------SYYDSSAYSVDRIIVHPDYSSQTN-SND 350

  Fly   367 IALVRLQTPVRYTHEILPICVPKDPIPL-HNHPLQIAGWGYTKNR-------EYSQV-LLHNTVY 422
            |||::|:|.:.::....|:|:|...:.. ...|..|:|||.|..:       :|:.| |:..|.
 Frog   351 IALMKLKTSIAFSSISRPVCLPNYGMQWEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTT- 414

  Fly   423 ENRYYCQDKISF--FRNESQICASGIR-GEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSEN 484
                 |...|.:  ....|.|||...: |.|||:|||||||:...|:    :.:|.|..|:|...
 Frog   415 -----CNQTIMYNGAITSSMICAGYPKGGVDSCQGDSGGPLVTKTNS----LWWLVGDTSWGDGC 470

  Fly   485 CGDRKPGVYTKTGAFFSWI 503
            ....:||||.....|..||
 Frog   471 ANVYRPGVYGNMTVFLQWI 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	76/268 (28%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060	10/46 (22%)
		SRCR_2	160..255	CDD:464747	21/119 (18%)
		Tryp_SPc	261..489	CDD:238113	74/269 (28%)