DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10232 and proc.2

DIOPT Version :9

Sequence 1:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	94/332 - (28%)
Similarity:	143/332 - (43%)	Gaps:	53/332 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 DCPADEKCIRLDKCLRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLPTSCGQA 251
            |.|..|| ..::|....||   |.||::   |.....|.:...::.|.:...||.: ..|..|..
Frog   378 DDPTAEK-KPINKTSLDHN---EIGASV---RAARTGTSKSVWEENHGLASVEPDD-YNTPDGDV 434

  Fly   252 PPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLV 316
                |:..|......:.||. :||..||....    |.||||:.|:||:||||....       :
Frog   435 ----RIVGGMRCELGQCPWQ-VLIRNNRGFGF----CGGSLISSRWVLSAAHCFESQ-------I 483

  Fly   317 LRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNV--HEQYFNTSRFESDIALVRLQTPVRYT 379
            ...|.:|::| |...|.|          |..|....|  |..|. ...::.||||:.|::|..:.
Frog   484 PHHVTIGDYD-TYRRDMD----------EQKIAVLQVFSHPNYL-AEFYDHDIALLFLRSPAMFG 536

  Fly   380 HEILPICVPKDP-----IPLHNHPLQIAGWGYTKN-REYSQVLLH-NTVYENRYYCQDKISFFRN 437
            ....|||:| :|     :.......|::|||.|:. ..|::.||. .....::..|.........
Frog   537 EYSRPICLP-NPGLGKMLTQEGQTGQVSGWGATRQFGPYTRFLLKVRLPIVSQETCMASTENILT 600

  Fly   438 ESQICASGIRG-EDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDR-KPGVYTKTGAFF 500
            .:..||....| :|:|.||||||..:.    :.|..:|.|:||:| :.|.:: |.||||:...:.
Frog   601 GNMFCAGYKEGVKDACSGDSGGPFAVL----FHDTWFLVGVVSWG-DGCAEKGKYGVYTRVANYM 660

  Fly   501 SWIKANL 507
            .|||..:
Frog   661 PWIKETI 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	76/256 (30%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	73/253 (29%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	76/259 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920