DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and PDR17

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_014135.1	Gene:	PDR17 / 855457	SGDID:	S000005208	Length:	350	Species:	Saccharomyces cerevisiae

Alignment Length:	226	Identity:	52/226 - (23%)
Similarity:	88/226 - (38%)	Gaps:	62/226 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TDEQLILAFLRRCRFSQEETKRRFDNYYSLRSVFPEVLGSRQVDEALLTQLQRGIHVI-PMRPVS 111
            |.:|:||.|        :..||..  ||        :...||..|:...|:|..:::: ....|:
Yeast   146 TGKQVILGF--------DNAKRPL--YY--------MKNGRQNTESSFRQVQELVYMMETATTVA 192

  Fly   112 PEGPR--VIISQFRN-----IDPKKSNPREAFKLIFIML-----ELLALECDNAAISGLIWVVDA 164
            |:|..  .::..|::     |...|:.|....::...::     |.|| :|....|....|..
Yeast   193 PQGVEKITVLVDFKSYKEPGIITDKAPPISIARMCLNVMQDHYPERLA-KCVLINIPWFAWAF-- 254

  Fly   165 RDVTMEQMMQYDPFL--LKKAFALVDQCIPLRFVEIHMINMRKEGQTIFNFVTKFLPSKLPFKFV 227
                  ..|.| |||  ..||.|:.|:  |.   |.|:...:.:  .::|.:..|     .:|..
Yeast   255 ------LKMMY-PFLDPATKAKAIFDE--PF---ENHIEPSQLD--ALYNGLLDF-----KYKHE 300

  Fly   228 VH-----KKSEDLYQHLPRDVMTIEYGGTNG 253
            |:     ||.:||  .|.|....:::||..|
Yeast   301 VYWPDMVKKVDDL--RLKRFDRFLKFGGIVG 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	38/175 (22%)
PDR17	NP_014135.1	CRAL_TRIO_N	49..115	CDD:397711
PDR17	NP_014135.1	CRAL_TRIO	146..291	CDD:395525	39/179 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343332
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930