DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and Ttpal

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_083788.2	Gene:	Ttpal / 76080	MGIID:	1923330	Length:	343	Species:	Mus musculus

Alignment Length:	283	Identity:	72/283 - (25%)
Similarity:	132/283 - (46%)	Gaps:	29/283 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TLDPKLAALAKSECNEEQAQRAEIIATIKTWITKS-PHLKAPTDEQLILAFLRRCRFSQEETKRR 70
            :|...|...|:.|..|:...|...:..::..:.|. |:|....|:..:|.|||..:|..:...:.
Mouse    35 SLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQL 99

  Fly    71 FDNYYSLRSVFPEVLGSRQ-------VDEALLTQL----QRGIHVIPMRPVSPEGPRVIISQFRN 124
            ..||:..|..:|||..:.:       ::...||.|    .||.||:.:||     .|.|.|.:
Mouse   100 LVNYHGCRRSWPEVFSNLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRP-----DRWIPSNY-- 157

  Fly   125 IDPKKSNPREAFKLIFIMLELLALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQ 189
              |...|    .:.:::.||.| ::.:...::|::.:.|.:.|::.:...:.||:.||...::..
Mouse   158 --PITEN----IRAVYLTLEKL-IQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQD 215

  Fly   190 CIPLRFVEIHMINMRKEGQTIFNFVTKFLPSKLPFKFVVHKKS-EDLYQHLPRDVMTIEYGGTNG 253
            ..|:|...:|::|..:..:.||..:..||..|:..:|.:|... ..|:.:|||:::..|||||.|
Mouse   216 GFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYGGTAG 280

  Fly   254 YQAEAVDHWRQKLLDSKDYLAKD 276
            ....|  .|...||.|::...|:
Mouse   281 ELDTA--SWNAVLLASEEDFVKE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	42/160 (26%)
Ttpal	NP_083788.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		CRAL_TRIO_N	57..103	CDD:215024	9/45 (20%)
		SEC14	122..278	CDD:238099	42/169 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910