DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10300 and Clvs1

DIOPT Version :9

Sequence 1:	NP_651174.2	Gene:	CG10300 / 42798	FlyBaseID:	FBgn0039107	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	281	Identity:	64/281 - (22%)
Similarity:	117/281 - (41%)	Gaps:	28/281 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LDPKLAALAKSECNEEQAQRAEIIATIKTWITKSPHLK-APTDEQLILAFLRRCRFSQEETKRRF 71
            |.|.....|:.|.||......:.|..::..|...|.:. ..||:..||.|||..:|.|.:..|..
Mouse    30 LSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLL 94

  Fly    72 DNYYSLRSVFPEVLGSRQVDE-----ALLT----QLQRGIHVIPMRPVSPEGPRVIISQFRNIDP 127
            ..|:..|.:..::..:.:.|:     ||:.    .|:...|.         |.::::....|.|.
Mouse    95 AQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPGVLENRDHY---------GRKILLLFAANWDQ 150

  Fly   128 KKSNPREAFKLIFIMLELLALECDNAAISGLIWVVDARDVTMEQMMQYDPFLLKKAFALVDQCIP 192
            .:::..:..:.|.:.||:| :|.....|:|.|.::|..:.:.:|..:..|.:||.|...:....|
Mouse   151 SRNSFTDILRAILLSLEVL-IEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFP 214

  Fly   193 LRFVEIHMINMRKEGQTIFNFVTKFLPSKLPFKFVVHKKS-EDLYQHLPRDVMTIEYGGTNGYQA 256
            .||..:|.:|.......::..:..||..|...:..:|..: ..|:|.:..:.:..|:|||  ...
Mouse   215 ARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGT--LPP 277

  Fly   257 EAVDHWRQKLL-----DSKDY 272
            ..:..|.:.||     |..||
Mouse   278 YDMGTWARTLLGPDYSDENDY 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10300	NP_651174.2	SEC14	95..251	CDD:238099	32/160 (20%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	13/45 (29%)
		CRAL_TRIO	125..274	CDD:366224	32/158 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835963
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750